Pathogenesis of human cytomegalovirus in the immunocompromised host

P Griffiths, M Reeves - Nature Reviews Microbiology, 2021 - nature.com
Human cytomegalovirus (HCMV) is a herpesvirus that infects~ 60% of adults in developed
countries and more than 90% in developing countries. Usually, it is controlled by a vigorous …

Asymmetric organocatalysis: an enabling technology for medicinal chemistry

B Han, XH He, YQ Liu, G He, C Peng… - Chemical Society Reviews, 2021 - pubs.rsc.org
The efficacy and synthetic versatility of asymmetric organocatalysis have contributed
enormously to the field of organic synthesis since the early 2000s. As asymmetric …

Herpesvirus latency

JI Cohen - The Journal of clinical investigation, 2020 - Am Soc Clin Investig
Herpesviruses infect virtually all humans and establish lifelong latency and reactivate to
infect other humans. Latency requires multiple functions: maintaining the herpesvirus …

Dendritic cells and the control of immunity

J Banchereau, RM Steinman - Nature, 1998 - nature.com
B and T lymphocytes are the mediators of immunity, but their function is under the control of
dendritic cells. Dendritic cells in the periphery capture and process antigens, express …

Immunobiology of dendritic cells

J Banchereau, F Briere, C Caux… - Annual review of …, 2000 - annualreviews.org
Dendritic cells (DCs) are antigen-presenting cells with a unique ability to induce primary
immune responses. DCs capture and transfer information from the outside world to the cells …

Diagnosis and management of human cytomegalovirus infection in the mother, fetus, and newborn infant

MG Revello, G Gerna - Clinical microbiology reviews, 2002 - Am Soc Microbiol
Human cytomegalovirus (HCMV) is the leading cause of congenital viral infection and
mental retardation. HCMV infection, while causing asymptomatic infections in most …

Natural killer cells, viruses and cancer

A Cerwenka, LL Lanier - Nature reviews immunology, 2001 - nature.com
Natural killer cells are innate immune cells that control certain microbial infections and
tumours. The function of natural killer cells is regulated by a balance between signals …

Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments

MK Gandhi, R Khanna - The Lancet infectious diseases, 2004 - thelancet.com
After initial infection, human cytomegalovirus remains in a persistent state with the host.
Immunity against the virus controls replication, although intermitent viral shedding can still …

Consensus on the role of human cytomegalovirus in glioblastoma

K Dziurzynski, SM Chang, AB Heimberger… - Neuro …, 2012 - academic.oup.com
The human cytomegalovirus (HCMV) and glioma symposium was convened on April 17,
2011 in Washington, DC, and was attended by oncologists and virologists involved in …

Cytomegalovirus remains latent in a common precursor of dendritic and myeloid cells

G Hahn, R Jores, ES Mocarski - Proceedings of the …, 1998 - National Acad Sciences
Hematopoietic cells and their progenitors play important roles in human cytomegalovirus
latency and reactivation. Latent infection has been evaluated in defined populations of …