Leveraging human–mouse studies to advance the genetics of hearing impairment in Africa
K James, OG Oluwole - The Journal of Gene Medicine, 2024 - Wiley Online Library
Mouse models are used extensively to understand human pathobiology and mechanistic
functions of disease‐associated loci. However, in this review, we investigate the potential of …
functions of disease‐associated loci. However, in this review, we investigate the potential of …
[HTML][HTML] An evidence-based systematic review of pleiotropic potential health benefits of sorghum bicolor supplement: A polyphenol-rich derivative of the leaf sheaths of …
A Adebesin, AI Omogbiya… - Journal of Natural …, 2024 - informaticsjournals.co.in
Globally, across different cultures, humans have historically depended largely on medicinal
plants for managing diseases that have hitherto threatened their optimal health, survival …
plants for managing diseases that have hitherto threatened their optimal health, survival …
Comparison of microwave and high‐pressure processing on bound phenolic composition and antioxidant activities of sorghum hull
M Luo, F Hou, L Dong, F Huang… - International Journal of …, 2020 - Wiley Online Library
The influence of microwave boiling (MB treated 5, 10 and 15 s was abbreviated as MB5,
MB10 and MB15, respectively) and high‐pressure boiling (HB processed 10, 20 and 30 min …
MB10 and MB15, respectively) and high‐pressure boiling (HB processed 10, 20 and 30 min …
Apigenin and apigeninidin isolates from the Sorghum bicolor leaf targets inflammation via cyclo‐oxygenase‐2 and prostaglandin‐E2 blockade
SBL Makanjuola, AO Ogundaini… - … journal of rheumatic …, 2018 - Wiley Online Library
Aim This study evaluated the anti‐inflammatory properties of a species of Sorghum bicolor
leaf (SBL) grown in West Africa. Method Cyclo‐oxygenase (COX)‐2: COX‐1 selectivity …
leaf (SBL) grown in West Africa. Method Cyclo‐oxygenase (COX)‐2: COX‐1 selectivity …
[HTML][HTML] Periodontitis increases rheumatic factor serum levels and citrullinated proteins in gingival tissues and alter cytokine balance in arthritic rats
MG Corrêa, SB Sacchetti, FV Ribeiro, SP Pimentel… - PloS one, 2017 - journals.plos.org
This study investigated some immunological features by experimental periodontitis (EP) and
rheumatoid arthritis (RA) disease interact in destructive processes in arthritic rats. Rats were …
rheumatoid arthritis (RA) disease interact in destructive processes in arthritic rats. Rats were …
Storage stability of sorghum phenolic extracts' flavones luteolin and apigenin
J Bradwell, M Hurd, P Pangloli, A McClure, VP Dia - Lwt, 2018 - Elsevier
Sorghum is an important crop with reported health-promoting properties. The objective was
to determine the stability of two major flavones in sorghum phenolic extract as affected by pH …
to determine the stability of two major flavones in sorghum phenolic extract as affected by pH …
[HTML][HTML] Jobelyn® attenuates inflammatory responses and neurobehavioural deficits associated with complete Freund-adjuvant-induced arthritis in mice
Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects the physical and
psychosocial wellbeing of the patients and a major cause of work disability. Current drugs …
psychosocial wellbeing of the patients and a major cause of work disability. Current drugs …
Sorghum bicolor polyphenol-rich extract improves insulin sensitivity and protect against chronic stress exacerbated diabetic nephropathy through modulation of Nrf2 …
Introduction Sorghum bicolor leaf sheath is known for its rich phytoconstituents 3-in
deoxyanthocyanidins with protective and health benefits in targeting oxidative stress …
deoxyanthocyanidins with protective and health benefits in targeting oxidative stress …
[HTML][HTML] Effects of Jobelyn® on isoniazid-induced seizures, biomarkers of oxidative stress and glutamate decarboxylase activity in mice
Methods: A total of 6 mice received JB (10–50 mg/kg, PO), pyridoxine (300 mg/kg),
diazepam (5 mg/kg), or distilled water (10 mL/kg) 30 minutes prior to the induction of SE with …
diazepam (5 mg/kg), or distilled water (10 mL/kg) 30 minutes prior to the induction of SE with …
Jobelyn suppresses hippocampal neuronal apoptosis and necrosis in experimental alcohol-induced brain stress
Neurodegeneration in the hippocampus is a consequence of alcohol abuse which
compromises the survival of the CNS tissue and its self-renewal capacity. So far …
compromises the survival of the CNS tissue and its self-renewal capacity. So far …