State-of-the-art review of theabrownins: from preparation, structural characterization to health-promoting benefits

L Cheng, Y Wei, L Peng, K Wei, Z Liu… - Critical Reviews in Food …, 2023 - Taylor & Francis
As far as health benefit is concerned, dark tea is one of the best beverages in the world.
Theabrownins are the major ingredient contributing to the health benefits of dark tea and …

Possible mechanisms of dark tea in cancer prevention and management: a comprehensive review

H Deng, J Liu, Y Xiao, JL Wu, R Jiao - Nutrients, 2023 - mdpi.com
Tea is one of the most popular drinks in the world. Dark tea is a kind of post-fermented tea
with unique sensory characteristics that is produced by the special fermentation of …

Theabrownin from Fu brick tea improves ulcerative colitis by shaping the gut microbiota and modulating the tryptophan metabolism

W Yang, D Ren, H Shao, X Zhang, T Li… - Journal of Agricultural …, 2023 - ACS Publications
Fu brick tea theabrownin (FBTB) is a kind of biomacromolecule produced by oxidative
polymerization of tea polyphenols. Although a variety of diseases can be alleviated by TB, its …

Vitamin K2 supplementation improves impaired glycemic homeostasis and insulin sensitivity for type 2 diabetes through gut microbiome and fecal metabolites

Y Zhang, L Liu, C Wei, X Wang, R Li, X Xu, Y Zhang… - BMC medicine, 2023 - Springer
Background There is insufficient evidence for the ability of vitamin K2 to improve type 2
diabetes mellitus symptoms by regulating gut microbial composition. Herein, we aimed to …

mTOR signaling pathway and gut microbiota in various disorders: Mechanisms and potential drugs in pharmacotherapy

Y Gao, T Tian - International Journal of Molecular Sciences, 2023 - mdpi.com
The mammalian or mechanistic target of rapamycin (mTOR) integrates multiple intracellular
and extracellular upstream signals involved in the regulation of anabolic and catabolic …

Regulation of the intestinal flora using polysaccharides from Callicarpa nudiflora Hook to alleviate ulcerative colitis and the molecular mechanisms involved

X Qin, K Nong, Z Liu, X Fang, B Zhang, W Chen… - International Journal of …, 2024 - Elsevier
Ulcerative colitis (UC) is a type of inflammatory bowel disease (IBD) that cannot be
completely cured by current treatments. C. nudiflora Hook has antibacterial, anti …

[HTML][HTML] The interactions between traditional Chinese medicine and gut microbiota in cancers: current status and future perspectives

X Wei, F Wang, P Tan, H Huang, Z Wang, J Xie… - Pharmacological …, 2024 - Elsevier
The gut microbiota, known as the “forgotten organ” and “human second genome,” comprises
a complex microecosystem. It significantly influences the development of various tumors …

Mechanic evaluation of Wu-Mei-Pill on colitis-associated colorectal cancer: An integrated transcriptomics, metabolomics, and experimental validation study

H Cui, Y Jin, N Wang, H Liu, R Shu, J Wang, X Wang… - Phytomedicine, 2024 - Elsevier
Background Chronic intestinal inflammatory diseases play a crucial role in the onset of
colorectal cancer (CRC). Effectively impeding the progression of colitis-associated colorectal …

Freeze-dried jaboticaba (Myrciaria jaboticaba) peel powder, a rich source of anthocyanins and phenolic acids, mitigates inflammation-driven colorectal cancer in mice

RP do Nascimento, JS Rizzato, G Polezi, AMTM Moya… - Food Bioscience, 2023 - Elsevier
This study aimed to characterize the peel of jaboticaba (Myrciaria jaboticaba (Vell.) O. Berg)
by spectrophotometry and chromatography, and investigate its effects on mice with …

Murine models of colorectal cancer: the azoxymethane (AOM)/dextran sulfate sodium (DSS) model of colitis-associated cancer

D Dzhalilova, N Zolotova, N Fokichev, O Makarova - PeerJ, 2023 - peerj.com
Background Colorectal cancer (CRC) is the third most common cancer. It is a
heterogeneous disease, including both hereditary and sporadic types of tumors. CRC …