Membranous nephropathy: mechanistic insights and therapeutic perspectives

MR Hua, YL Zhao, JZ Yang, L Zou, YY Zhao… - International …, 2023 - Elsevier
Membranous nephropathy (MN) is one of the most common causes of non-diabetic
nephrotic syndrome in adults. About 80% of cases are renal limited (primary MN) and 20 …

[HTML][HTML] Membranous nephropathy: systems biology-based novel mechanism and traditional Chinese medicine therapy

H Miao, Y Zhang, X Yu, L Zou, Y Zhao - Frontiers in Pharmacology, 2022 - frontiersin.org
Membranous nephropathy (MN) is a renal-limited non-inflammatory autoimmune disease in
the glomerulus, which is the second or third main cause of end-stage kidney diseases in …

[HTML][HTML] Helper T cells in idiopathic membranous nephropathy

Q Zhao, H Dai, X Liu, H Jiang, W Liu, Z Feng… - Frontiers in …, 2021 - frontiersin.org
Idiopathic membranous nephropathy (IMN) is an autoimmune disease in which the immune
system produces an antibody response to its own antigens due to impaired immune …

Cytokines network in primary membranous nephropathy

Q Zhao, H Dai, Y Hu, H Jiang, Z Feng, W Liu… - International …, 2022 - Elsevier
There have been extensive studies on the immunological mechanism of primary
membranous nephropathy (PMN). Autoantibodies, being the end product of humoral auto …

[HTML][HTML] Membranous nephropathy: Clearer pathology and mechanisms identify potential strategies for treatment

EYM Chung, YM Wang, K Keung, M Hu… - Frontiers in …, 2022 - frontiersin.org
Primary membranous nephropathy (PMN) is one of the common causes of adult-onset
nephrotic syndrome and is characterized by autoantibodies against podocyte antigens …

[HTML][HTML] B cells in primary membranous nephropathy: escape from immune tolerance and implications for patient management

BYF So, DYH Yap, TM Chan - International Journal of Molecular Sciences, 2021 - mdpi.com
Membranous nephropathy (MN) is an important cause of nephrotic syndrome and chronic
kidney disease (CKD) in adults. The pathogenic significance of B cells in MN is increasingly …

[HTML][HTML] Identification of molecular mechanism and key biomarkers in membranous nephropathy by bioinformatics analysis

Z Dong, Y Geng, P Zhang, J Tang, Z Cao… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Objectives: Membranous nephropathy (MN) is an autoimmune nephropathy. The incidence
of MN is increasing gradually in recent years. Previous studies focused on antibody …

[HTML][HTML] Exploring the differences in molecular mechanisms and key biomarkers between membranous nephropathy and lupus nephritis using integrated …

Z Dong, H Dai, W Liu, H Jiang, Z Feng, F Liu… - Frontiers in …, 2022 - frontiersin.org
Background: Both membranous nephropathy (MN) and lupus nephritis (LN) are autoimmune
kidney disease. In recent years, with the deepening of research, some similarities have been …

Course monitoring of membranous nephropathy: Both autoantibodies and podocytes require multidimensional attention

W Liu, G Huang, H Rui, J Geng, H Hu, Y Huang… - Autoimmunity …, 2022 - Elsevier
A variety of podocyte antigens have been identified in human membranous nephropathy
(MN), which is divided into various antigen-dominated subtypes, confirming the concept that …

Molecular characteristics of circulating B cells and kidney cells at the single-cell level in special types of primary membranous nephropathy

X Feng, Q Chen, J Zhong, S Yu, Y Wang… - Clinical Kidney …, 2023 - academic.oup.com
Background Although primary membranous nephropathy (pMN) associated with podocyte
autoantibodies (POS) is becoming well-known, the molecular characteristics of the specific …