All cellular compartments are separated from the external environment by a membrane,
which consists of a lipid bilayer. Subcellular structures, including clathrin-coated pits …

Actin filament assembly typically occurs in association with cellular membranes. A large
number of proteins sit at the interface between actin networks and membranes, playing …

Innate immunity provides essential protection against life-threatening fungal infections.
However, the outcomes of individual skirmishes between immune cells and fungal …

Brain somatic mutations confer genomic diversity in the human brain and cause
neurodevelopmental disorders. Recently, brain somatic activating mutations in MTOR have …

It is unclear whether the establishment of apical–basal cell polarity during the generation of
epithelial lumens requires molecules acting at the plasma membrane/actin interface. Here …

Lipid membranes are structural components of cell surfaces and intracellular organelles.
Alterations in lipid membrane shape are accompanied by numerous cellular functions …

Filopodia are precursors of dendritic spines and polarized cell migration. The I-BAR-domain
protein IRSp53 is a key regulator of filopodia dynamics that couples Rho-GTPase signaling …

Filopodia are actin-filled membrane protrusions that play essential roles in cell motility and
cell–cell communication and act as precursors of dendritic spines. IRSp53 is an essential …

Podosomes and invadopodia (collectively known as invadosomes) are specialized plasma-
membrane actin-based microdomains that combine adhesive properties with matrix …

Invadosomes are actin-based structures involved in extracellular-matrix degradation.
Invadosomes, either known as podosomes or invadopodia, are found in an increasing …