Dynamic shaping of cellular membranes by phospholipids and membrane-deforming proteins
S Suetsugu, S Kurisu, T Takenawa - Physiological reviews, 2014 - journals.physiology.org
All cellular compartments are separated from the external environment by a membrane,
which consists of a lipid bilayer. Subcellular structures, including clathrin-coated pits …
which consists of a lipid bilayer. Subcellular structures, including clathrin-coated pits …
BAR domain proteins—a linkage between cellular membranes, signaling pathways, and the actin cytoskeleton
PJ Carman, R Dominguez - Biophysical reviews, 2018 - Springer
Actin filament assembly typically occurs in association with cellular membranes. A large
number of proteins sit at the interface between actin networks and membranes, playing …
number of proteins sit at the interface between actin networks and membranes, playing …
Immune cells fold and damage fungal hyphae
JM Bain, MF Alonso, DS Childers… - Proceedings of the …, 2021 - National Acad Sciences
Innate immunity provides essential protection against life-threatening fungal infections.
However, the outcomes of individual skirmishes between immune cells and fungal …
However, the outcomes of individual skirmishes between immune cells and fungal …
Brain somatic mutations in MTOR reveal translational dysregulations underlying intractable focal epilepsy
Brain somatic mutations confer genomic diversity in the human brain and cause
neurodevelopmental disorders. Recently, brain somatic activating mutations in MTOR have …
neurodevelopmental disorders. Recently, brain somatic activating mutations in MTOR have …
IRSp53 controls plasma membrane shape and polarized transport at the nascent lumen in epithelial tubules
S Bisi, S Marchesi, A Rizvi, D Carra… - Nature …, 2020 - nature.com
It is unclear whether the establishment of apical–basal cell polarity during the generation of
epithelial lumens requires molecules acting at the plasma membrane/actin interface. Here …
epithelial lumens requires molecules acting at the plasma membrane/actin interface. Here …
Membrane re-modelling by BAR domain superfamily proteins via molecular and non-molecular factors
T Nishimura, N Morone… - Biochemical Society …, 2018 - portlandpress.com
Lipid membranes are structural components of cell surfaces and intracellular organelles.
Alterations in lipid membrane shape are accompanied by numerous cellular functions …
Alterations in lipid membrane shape are accompanied by numerous cellular functions …
Mechanism of IRSp53 inhibition by 14-3-3
DJ Kast, R Dominguez - Nature communications, 2019 - nature.com
Filopodia are precursors of dendritic spines and polarized cell migration. The I-BAR-domain
protein IRSp53 is a key regulator of filopodia dynamics that couples Rho-GTPase signaling …
protein IRSp53 is a key regulator of filopodia dynamics that couples Rho-GTPase signaling …
IRSp53 coordinates AMPK and 14-3-3 signaling to regulate filopodia dynamics and directed cell migration
DJ Kast, R Dominguez - Molecular biology of the cell, 2019 - Am Soc Cell Biol
Filopodia are actin-filled membrane protrusions that play essential roles in cell motility and
cell–cell communication and act as precursors of dendritic spines. IRSp53 is an essential …
cell–cell communication and act as precursors of dendritic spines. IRSp53 is an essential …
Importance of RhoGTPases in formation, characteristics, and functions of invadosomes
P Spuul, P Ciufici, V Veillat, A Leclercq, T Daubon… - Small …, 2014 - Taylor & Francis
Podosomes and invadopodia (collectively known as invadosomes) are specialized plasma-
membrane actin-based microdomains that combine adhesive properties with matrix …
membrane actin-based microdomains that combine adhesive properties with matrix …
Cdc42 and Tks5: a minimal and universal molecular signature for functional invadosomes
J Di Martino, L Paysan, C Gest, V Lagrée… - Cell adhesion & …, 2014 - Taylor & Francis
Invadosomes are actin-based structures involved in extracellular-matrix degradation.
Invadosomes, either known as podosomes or invadopodia, are found in an increasing …
Invadosomes, either known as podosomes or invadopodia, are found in an increasing …