Metalloproteases/anti-metalloproteases imbalance in chronic obstructive pulmonary disease: genetic factors and treatment implications
E Mocchegiani, R Giacconi… - Current opinion in …, 2011 - journals.lww.com
The disease is mainly caused by exposure to cigarette smoke or noxious gases and air
pollutants, but also genetic factors are involved. Among them, polymorphisms of MMPs …
pollutants, but also genetic factors are involved. Among them, polymorphisms of MMPs …
Xuanbai Chengqi decoction ameliorates pulmonary inflammation via reshaping gut microbiota and rectifying Th17/Treg imbalance in a murine model of chronic …
Y Wang, N Li, Q Li, Z Liu, Y Li, J Kong… - … journal of chronic …, 2021 - Taylor & Francis
Purpose Chronic obstructive pulmonary disease (COPD), a prevalent obstructive airway
disease, has become the third most common cause of death globally. Xuanbai Chengqi …
disease, has become the third most common cause of death globally. Xuanbai Chengqi …
Genomics of chronic obstructive pulmonary disease (COPD); exploring the SNPs of protease-antiprotease pathway
M Kumar, N Phougat, S Ruhil, S Dhankhar… - Current …, 2013 - ingentaconnect.com
The COPD has been an important respiratory condition that affects people worldwide and its
incidence has been alarming. The increasing incidence of this disorder has been attributed …
incidence has been alarming. The increasing incidence of this disorder has been attributed …
Epigenome-wide association study of chronic obstructive pulmonary disease and lung function in Koreans
Aim: To identify differentially methylated probes (DMPs) and regions (DMRs) in relation to
chronic obstructive pulmonary disease (COPD) and lung function traits. Methods: We …
chronic obstructive pulmonary disease (COPD) and lung function traits. Methods: We …
[HTML][HTML] Association of COL4A3 (rs55703767), MMP-9 (rs17576) and TIMP-1 (rs6609533) gene polymorphisms with susceptibility to type 2 diabetes
S Saravani, D Yari, R Saravani… - Biomedical …, 2017 - spandidos-publications.com
Abstract Type 2 diabetes (T2D) is defined by high levels of glucose in the blood. The
collagen IV level is associated with conditions of hyperglycemia and insulin resistance …
collagen IV level is associated with conditions of hyperglycemia and insulin resistance …
[HTML][HTML] The 372 T/C genetic polymorphism of TIMP-1 is associated with serum levels of TIMP-1 and survival in patients with severe sepsis
L Lorente, M Martín, F Plasencia, J Solé-Violán… - Critical Care, 2013 - Springer
Introduction Previous studies have found higher circulating levels of tissue inhibitor of matrix
metalloproteinase (TIMP)-1 in nonsurviving septic patients than in surviving septic patients …
metalloproteinase (TIMP)-1 in nonsurviving septic patients than in surviving septic patients …
[HTML][HTML] The role of the liver X receptor in chronic obstructive pulmonary disease
Background There is a need for novel anti-inflammatory therapies to treat COPD. The liver X
receptor (LXR) is a nuclear hormone receptor with anti-inflammatory properties. Methods We …
receptor (LXR) is a nuclear hormone receptor with anti-inflammatory properties. Methods We …
[HTML][HTML] Polymorphisms in myeloperoxidase and tissue inhibitor of metalloproteinase-1 genes and their association with preeclampsia in the Chinese Han population
L Liu, D He, W Zhou, Z Guo, Y Ma, L Liu, H He, S He… - Heliyon, 2024 - cell.com
Hypertensive disorders of pregnancy (HDP) are multifaceted syndromes unique to
pregnancy, characterized by increased blood pressure, edema, and proteinuria. Patients …
pregnancy, characterized by increased blood pressure, edema, and proteinuria. Patients …
Identification of MMP-9 as a biomarker for detecting progression of chronic obstructive pulmonary disease
MF Abd El-Fatah, MA Ghazy… - … and Cell Biology, 2015 - cdnsciencepub.com
Chronic obstructive pulmonary disease (COPD) is a complex immunological disease with
multiple pathological features that is primarily induced by smoking together with additional …
multiple pathological features that is primarily induced by smoking together with additional …
[HTML][HTML] EGFR and MMP-9 are associated with neointimal hyperplasia in systemic-to-pulmonary shunts in children with complex cyanotic heart disease
P Kottmann, K Eildermann, SR Murthi, J Cleuziou… - Mammalian …, 2023 - Springer
Systemic-to-pulmonary shunt malfunction contributes to morbidity in children with complex
congenital heart disease after palliative procedure. Neointimal hyperplasia might play a role …
congenital heart disease after palliative procedure. Neointimal hyperplasia might play a role …