Medicinal chemistry of oxazines as promising agents in drug discovery
Oxazines have brought much synthetic interest due to their extensive biological activities.
These are the important category of heterocycles, which may be formally derived from …
These are the important category of heterocycles, which may be formally derived from …
Advances in the chemical and biological diversity of heterocyclic systems incorporating pyrimido [1, 6-a] pyrimidine and pyrimido [1, 6-c] pyrimidine scaffolds
Heterocycles incorporating a pyrimidopyrimidine scaffold have aroused great interest from
researchers in the field of medical chemistry because of their privileged biological activities; …
researchers in the field of medical chemistry because of their privileged biological activities; …
Methods of synthesis for the azolo [1, 2, 4] triazines
EK Voinkov, RA Drokin, EN Ulomsky… - Chemistry of …, 2020 - Springer
The review summarizes and analyzes data from modern information sources on the
methods of synthesis of azolo [X, Yc][1, 2, 4] triazines. Approaches to the construction of the …
methods of synthesis of azolo [X, Yc][1, 2, 4] triazines. Approaches to the construction of the …
Recent advances in 1, 2, 4-triazolo [1, 5-a] pyrimidine chemistry
G Fischer - Advances in Heterocyclic Chemistry, 2019 - Elsevier
The review deals with the pharmaceutically and agrochemically important group of 1, 2, 4-
triazolo [1, 5-a] pyrimidines (TPs) and covers relevant literature published from about 2006 …
triazolo [1, 5-a] pyrimidines (TPs) and covers relevant literature published from about 2006 …
The most recent compilation of reactions of enaminone derivatives with various amine derivatives to generate biologically active compounds
TA Farghaly, AM Alosaimy… - Mini Reviews in …, 2024 - ingentaconnect.com
Heterocyclic derivatives serve as the fundamental components of both natural and synthetic
drugs. Enaminones play a crucial role as foundational units in the synthesis of numerous …
drugs. Enaminones play a crucial role as foundational units in the synthesis of numerous …
Stereoselective Oxidative Cyclization of N-Allyl Benzamides to Oxaz(ol)ines
AH Abazid, TN Hollwedel, BJ Nachtsheim - Organic letters, 2021 - ACS Publications
This study presents an enantioselective oxidative cyclization of N-allyl carboxamides via a
chiral triazole-substituted iodoarene catalyst. The method allows the synthesis of highly …
chiral triazole-substituted iodoarene catalyst. The method allows the synthesis of highly …
Design and Synthesis of Some New Quinoxaline‐Based Heterocycles
IH El Azab, NAA Elkanzi… - Journal of Heterocyclic …, 2018 - Wiley Online Library
Considering quinoxaline as a privileged structure for developing probes of impressive
therapeutic potentials, some new azole and azine conjugates of quinoxaline were …
therapeutic potentials, some new azole and azine conjugates of quinoxaline were …
4‐Chlorothiazole‐5‐carbaldehydes as Potent Precursors for Synthesis of Some New Pendant N‐heterocyces Endowed with Anti‐Tumor Activity
IH El Azab, AA Gobouri… - Journal of Heterocyclic …, 2019 - Wiley Online Library
In our approach to synthesize bioactive molecules, a series of novel N‐heterocycles were
synthesized and evaluated for their in vitro antitumor activity against a panel of three human …
synthesized and evaluated for their in vitro antitumor activity against a panel of three human …
Recent Developments in the Antimicrobial Potential of Some Nitrogenous Heterocycles and their SAR Studies: A Review
B Nehra, M Kumar, S Singh, V Chawla… - Current Medicinal …, 2024 - ingentaconnect.com
Background: Infection remains a significant global health concern, with millions of new
cases and deaths occurring due to infectious diseases. Currently, chemoprophylaxis and …
cases and deaths occurring due to infectious diseases. Currently, chemoprophylaxis and …
Recent Synthetic Approaches to N, N-Dimethyl-β-Ketoenamines
HM Gaber, ZA Muhammad, SM Gomha… - Current Organic …, 2017 - ingentaconnect.com
Background: N, N-dimethyl-β-ketoenamines have proven to be of biological interest and
provide an access to new class of biologically active heterocyclic compounds for biomedical …
provide an access to new class of biologically active heterocyclic compounds for biomedical …