[HTML][HTML] The trilateral interactions between mammalian target of rapamycin (mTOR) signaling, the circadian clock, and psychiatric disorders: an emerging model
Abstract Circadian (~ 24 h) rhythms in physiology and behavior are evolutionarily conserved
and found in almost all living organisms. The rhythms are endogenously driven by daily …
and found in almost all living organisms. The rhythms are endogenously driven by daily …
[HTML][HTML] Implication of hippocampal neurogenesis in autism spectrum disorder: Pathogenesis and therapeutic implications
C Liu, J Liu, H Gong, T Liu, X Li… - Current …, 2023 - ncbi.nlm.nih.gov
Autism spectrum disorder (ASD) is a cluster of heterogeneous neurodevelopmental
conditions with atypical social communication and repetitive sensory-motor behaviors. The …
conditions with atypical social communication and repetitive sensory-motor behaviors. The …
[HTML][HTML] SHANK2 Mutations Result in Dysregulation of the ERK1/2 Pathway in Human Induced Pluripotent Stem Cells-Derived Neurons and Shank2(−/−) Mice
AK Lutz, A Pérez Arévalo, V Ioannidis… - Frontiers in Molecular …, 2021 - frontiersin.org
SHANK2 (ProSAP1) is a postsynaptic scaffolding protein of excitatory synapses in the
central nervous system and implicated in the development of autism spectrum disorders …
central nervous system and implicated in the development of autism spectrum disorders …
[HTML][HTML] Insights into the structure and function of the hippocampus: implications for the pathophysiology and treatment of autism spectrum disorder
J Long, H Li, Y Liu, X Liao, Z Tang, K Han… - Frontiers in …, 2024 - frontiersin.org
The hippocampus is one of the brain areas affected by autism spectrum disorder (ASD).
Individuals with ASD typically have impairments in hippocampus-dependent learning …
Individuals with ASD typically have impairments in hippocampus-dependent learning …
[HTML][HTML] Vinpocetine's immunomodulating, anti-oxidant, anti-inflammatory, ant-ifibrotic, and PDE inhibiting potencies ameliorate bleomycin-induced pulmonary fibrosis
Results: Vinpocetine dose-dependently ameliorates PF induced by bleomycin
administration since vinpocetine effectively restored the normal body weight gain rates …
administration since vinpocetine effectively restored the normal body weight gain rates …
[HTML][HTML] Influence of prenatal drug exposure, maternal inflammation, and parental aging on the development of autism spectrum disorder
A Sato, H Kotajima-Murakami, M Tanaka… - Frontiers in …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) affects reciprocal social interaction and produces abnormal
repetitive, restrictive behaviors and interests. The diverse causes of ASD are divided into …
repetitive, restrictive behaviors and interests. The diverse causes of ASD are divided into …
Fullerenols Ameliorate Social Deficiency and Rescue Cognitive Dysfunction of BTBR T+Itpr3tf/J Autistic-Like Mice
J Luo, Y Luo, M Zhao, Y Liu, J Liu, Z Du… - International Journal …, 2024 - Taylor & Francis
Background Autism Spectrum Disorder (ASD) is a neurodevelopmental condition that affects
social interaction and communication and can cause stereotypic behavior. Fullerenols, a …
social interaction and communication and can cause stereotypic behavior. Fullerenols, a …
Cilostazol as adjunctive therapy in treatment of children with autism spectrum disorders: a double-blind and placebo-controlled randomized trial
P Ebrahimi, H Seyedmirzaei, K Moradi… - International clinical …, 2023 - journals.lww.com
We aimed to evaluate cilostazol therapeutic effects on aberrant behaviors of autism
spectrum disorder (ASD) children and its safety profile in a double-blind, randomized clinical …
spectrum disorder (ASD) children and its safety profile in a double-blind, randomized clinical …
Reversal of electrophysiological and behavioral deficits mediated by 5-HT7 receptor upregulation following LP-211 treatment in an autistic-like rat model induced by …
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
alterations and imbalances in multiple brain neurochemical systems, particularly the …
alterations and imbalances in multiple brain neurochemical systems, particularly the …
[HTML][HTML] The anti-inflammatory properties of vinpocetine mediates its therapeutic potential in management of atherosclerosis
Atherosclerosis (AS) formation is enhanced by different mechanisms including cytokine
generation, vascular smooth muscle cell proliferation, and migration. One of the recent …
generation, vascular smooth muscle cell proliferation, and migration. One of the recent …