Antibiotic perturbations to the gut microbiome
Antibiotic-mediated perturbation of the gut microbiome is associated with numerous
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …
Progress in alternative strategies to combat antimicrobial resistance: Focus on antibiotics
Antibiotic resistance, and, in a broader perspective, antimicrobial resistance (AMR),
continues to evolve and spread beyond all boundaries. As a result, infectious diseases have …
continues to evolve and spread beyond all boundaries. As a result, infectious diseases have …
Unravelling the collateral damage of antibiotics on gut bacteria
Antibiotics are used to fight pathogens but also target commensal bacteria, disturbing the
composition of gut microbiota and causing dysbiosis and disease. Despite this well-known …
composition of gut microbiota and causing dysbiosis and disease. Despite this well-known …
Bioaccumulation of therapeutic drugs by human gut bacteria
Bacteria in the gut can modulate the availability and efficacy of therapeutic drugs. However,
the systematic mapping of the interactions between drugs and bacteria has only started …
the systematic mapping of the interactions between drugs and bacteria has only started …
Multimodal interactions of drugs, natural compounds and pollutants with the gut microbiota
AE Lindell, M Zimmermann-Kogadeeva… - Nature Reviews …, 2022 - nature.com
The gut microbiota contributes to diverse aspects of host physiology, ranging from
immunomodulation to drug metabolism. Changes in the gut microbiota composition are …
immunomodulation to drug metabolism. Changes in the gut microbiota composition are …
Defining and combating antibiotic resistance from One Health and Global Health perspectives
Several interconnected human, animal and environmental habitats can contribute to the
emergence, evolution and spread of antibiotic resistance, and the health of these contiguous …
emergence, evolution and spread of antibiotic resistance, and the health of these contiguous …
Drug combinations: a strategy to extend the life of antibiotics in the 21st century
Antimicrobial resistance threatens a resurgence of life-threatening bacterial infections and
the potential demise of many aspects of modern medicine. Despite intensive drug discovery …
the potential demise of many aspects of modern medicine. Despite intensive drug discovery …
Zinc-doped Prussian blue enhances photothermal clearance of Staphylococcus aureus and promotes tissue repair in infected wounds
J Li, X Liu, L Tan, Z Cui, X Yang, Y Liang, Z Li… - Nature …, 2019 - nature.com
The application of photothermal therapy to treat bacterial infections remains a challenge, as
the high temperatures required for bacterial elimination can damage healthy tissues. Here …
the high temperatures required for bacterial elimination can damage healthy tissues. Here …
Plasmid-mediated colistin-resistance genes: mcr
Colistin is regarded as a last-line drug against serious infections caused by multidrug-
resistant Gram-negative bacterial pathogens. Therefore, the emergence of mobile colistin …
resistant Gram-negative bacterial pathogens. Therefore, the emergence of mobile colistin …
Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …