Graceful healthy ageing and extended longevity is the most desired goal for human race.
The process of ageing is inevitable and has a profound impact on the gradual deterioration …

Comparing biomarker profiles measured at similar ages, but earlier in life, among
exceptionally long-lived individuals and their shorter-lived peers can improve our …

Purpose Outcomes of hip fractures in centenarians remain underreported owing to the small
number of patients reaching 100 years of age. This review aimed to determine outcomes of …

Multimorbidity is challenging for both patients and healthcare systems due to its increasing
prevalence and high impact on people's health and well-being. The risk of multimorbidity …

Everyone has a chronological age. Because survivorship declines relentlessly in
populations with age-specific death rates greater than zero, everyone also has a …

Mosaic loss of the Y chromosome (mLOY) is a common somatic mutation in the blood of
elderly men and several studies have found mLOY in blood cells to be associated with an …

Background It is unclear to what degree centenarians are successful agers. We assess
successful aging (SA) and its subtypes in a large Chinese sample. Methods Based on a …

Background Longevity, a hallmark of successful aging, is a multifactorial trait with influences
from birth onwards. However, limited evidence exists on the pathways linking diverse life …

The increasing aging of the human population is currently and for the coming decades a
major public health issue in many countries, requiring the implementation of global public …

Background Despite most centenarians facing age-related declines in functional and
cognitive capacities, the severity of these declines varies among individuals, as does the …