Significance: Reactive oxygen species (ROS) are well known to promote innate immune
responses during and in the absence of microbial infections. However, excessive or …

Despite its potential to cause significant morbidity in children, pediatric antiphospholipid
syndrome (APS) is an understudied condition. In this review, we will cover what is known …

One of the main groups of lipids is phospholipids, which are mainly involved in forming cell
membranes. Neoplastic processes such as cell replication have increased lipid synthesis …

The pathological features of antiphospholipid syndrome (APS) are related to the activity of
circulating antiphospholipid antibodies (aPLs) associated with vascular thrombosis and …

Antiphospholipid Syndrome (APS) is an autoimmune disease characterized by arterial
and/or venous thrombosis and/or pregnancy morbidity, associated with circulating …

Antiphospholipid antibodies (aPL) have been reported to activate platelets. This is
considered to be one of the pathogenic properties of aPL. Even though aPL heterogeneity is …

Essentials• Antiphospholipid antibodies (aPL) are heterogeneous and induce different
cellular responses.• We analyzed signaling events induced by different monoclonal and …

Antiphospholipid syndrome: an update for clinicians and scie... : Current Opinion in
Rheumatology Antiphospholipid syndrome: an update for clinicians and scientists : Current …

Pediatric antiphospholipid syndrome (APS) is a rare acquired multisystem autoimmune
thromboinflammatory condition characterized by thrombotic and non-thrombotic clinical …

Introduction: Even though our understanding of the antiphospholipid syndrome (APS) has
improved tremendously over the last decades, we are still not in a position to replace …