Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles

AP Singh, A Biswas, A Shukla, P Maiti - Signal transduction and …, 2019 - nature.com
The application of nanomedicines is increasing rapidly with the promise of targeted and
efficient drug delivery. Nanomedicines address the shortcomings of conventional therapy, as …

Managing diabetes with nanomedicine: challenges and opportunities

O Veiseh, BC Tang, KA Whitehead… - Nature Reviews Drug …, 2015 - nature.com
Nanotechnology-based approaches hold substantial potential for improving the care of
patients with diabetes. Nanoparticles are being developed as imaging contrast agents to …

Nonviral vectors for gene delivery

MA Mintzer, EE Simanek - Chemical reviews, 2009 - ACS Publications
Gene therapy has gained significant attention over the past two decades as a potential
method for treating genetic disorders such as severe combined immunodeficiency, 1 cystic …

Current status of polymeric gene delivery systems

TG Park, JH Jeong, SW Kim - Advanced drug delivery reviews, 2006 - Elsevier
Gene therapy provides great opportunities for treating diseases from genetic disorders,
infections and cancer. To achieve successful gene therapy, development of proper gene …

Progress in developing cationic vectors for non-viral systemic gene therapy against cancer

M Morille, C Passirani, A Vonarbourg, A Clavreul… - Biomaterials, 2008 - Elsevier
Initially, gene therapy was viewed as an approach for treating hereditary diseases, but its
potential role in the treatment of acquired diseases such as cancer is now widely …

Self-assembled hydrogel nanoparticles for drug delivery applications

C Gonçalves, P Pereira, M Gama - Materials, 2010 - mdpi.com
Hydrogel nanoparticles—also referred to as polymeric nanogels or macromolecular micelles—
are emerging as promising drug carriers for therapeutic applications. These nanostructures …

Molecular design of functional polymers for gene therapy

JH Jeong, SW Kim, TG Park - Progress in Polymer Science, 2007 - Elsevier
In the post genomic era, massive genetic information of the human being accelerates the
identification of target genes for treating various diseases. A wide range of nucleic acid …

Biological and biomaterial approaches for improved islet transplantation

AS Narang, RI Mahato - Pharmacological reviews, 2006 - ASPET
Islet transplantation may be used to treat type I diabetes. Despite tremendous progress in
islet isolation, culture, and preservation, the clinical use of this modality of treatment is …

Antidiabetic effect of Lactobacillus casei CCFM0412 on mice with type 2 diabetes induced by a high-fat diet and streptozotocin

P Chen, Q Zhang, H Dang, X Liu, F Tian, J Zhao… - Nutrition, 2014 - Elsevier
Objective The aim of this study was to evaluate the antidiabetic effects of Lactobacillus casei
CCFM0412 on mice with type 2 diabetes induced by a high-fat diet and streptozotocin …

Poly (lactide-co-glycolide)-Polymethacrylate Nanoparticles for Intramuscular Delivery of Plasmid Encoding Interleukin-10 to Prevent Autoimmune Diabetes in Mice

A Basarkar, J Singh - Pharmaceutical research, 2009 - Springer
Purpose Determine the efficiency of cationic nanoparticles prepared by blending poly
(lactide-co-glycolide; PLGA) and methacrylate copolymer (Eudragit® E100) to deliver a …