Human pluripotent stem cell mechanobiology: manipulating the biophysical microenvironment for regenerative medicine and tissue engineering applications
RG Ireland, CA Simmons - Stem Cells, 2015 - academic.oup.com
A stem cell in its microenvironment is subjected to a myriad of soluble chemical cues and
mechanical forces that act in concert to orchestrate cell fate. Intuitively, many of these …
mechanical forces that act in concert to orchestrate cell fate. Intuitively, many of these …
A minireview of microfluidic scaffold materials in tissue engineering
In 2020, nearly 107,000 people in the US needed a lifesaving organ transplant, but due to a
limited number of donors, only∼ 35% of them have actually received it. Thus, successful bio …
limited number of donors, only∼ 35% of them have actually received it. Thus, successful bio …
A hyperelastic model for simulating cells in flow
SJ Müller, F Weigl, C Bezold, C Bächer… - … and Modeling in …, 2021 - Springer
In the emerging field of 3D bioprinting, cell damage due to large deformations is considered
a main cause for cell death and loss of functionality inside the printed construct. Those …
a main cause for cell death and loss of functionality inside the printed construct. Those …
Applications of fiber lasers for the development of compact photonic devices
R Mary, D Choudhury, AK Kar - IEEE Journal of Selected …, 2014 - ieeexplore.ieee.org
Ultrafast fiber lasers, with their distinct features of high stability, superior beam quality,
compactness and power scalability have revolutionized a variety of applications, ranging …
compactness and power scalability have revolutionized a variety of applications, ranging …
Single‐cell encapsulation via click‐chemistry alters production of paracrine factors from neural progenitor cells
B Oh, V Swaminathan, A Malkovskiy… - Advanced …, 2020 - Wiley Online Library
Extracellular matrix (ECM) properties affect multiple cellular processes such as cell survival,
proliferation, and protein synthesis. Thus, a polymeric‐cell delivery system with the ability to …
proliferation, and protein synthesis. Thus, a polymeric‐cell delivery system with the ability to …
Compression generated by a 3D supracellular actomyosin cortex promotes embryonic stem cell colony growth and expression of Nanog and Oct4
J Du, Y Fan, Z Guo, Y Wang, X Zheng, C Huang… - Cell systems, 2019 - cell.com
Mechanical factors play critical roles in mammalian development. Here, we report that
colony-growing mouse embryonic stem cells (mESCs) generate significant tension on the …
colony-growing mouse embryonic stem cells (mESCs) generate significant tension on the …
Quantified forces between HepG2 hepatocarcinoma and WA07 pluripotent stem cells with natural biomaterials correlate with in vitro cell behavior
In vitro cell culture or tissue models that mimic in vivo cellular response have potential in
tissue engineering and regenerative medicine, and are a more economical and accurate …
tissue engineering and regenerative medicine, and are a more economical and accurate …
Artificial Neural Network-Aided Computational Approach for Mechanophenotyping of Biological Cells Using Atomic Force Microscopy
The artificial neural network (ANN) based models have shown the potential to provide
alternate data-driven solutions in disease diagnostics, cell sorting and overcoming AFM …
alternate data-driven solutions in disease diagnostics, cell sorting and overcoming AFM …
High-throughput assessment of mechanical properties of stem cell derived red blood cells, toward cellular downstream processing
E Guzniczak, M Mohammad Zadeh, F Dempsey… - Scientific reports, 2017 - nature.com
Stem cell products, including manufactured red blood cells, require efficient sorting and
purification methods to remove components potentially harmful for clinical application …
purification methods to remove components potentially harmful for clinical application …
Polyacrylamide hydrogels with rigidity-independent surface chemistry show limited long-term maintenance of pluripotency of human induced pluripotent stem cells on …
S Paiva, P Joanne, C Migdal, EL Soler… - ACS Biomaterials …, 2019 - ACS Publications
In general, cells are cultured and adapted to the in vitro rigidities of plastic or glass ranging
between 1 and 10 GPa, which is very far from physiological values that are mostly in the …
between 1 and 10 GPa, which is very far from physiological values that are mostly in the …