Mechanisms of antidepressant resistance

W El-Hage, S Leman, V Camus… - Frontiers in …, 2013 - frontiersin.org
Depression is one of the most frequent and severe mental disorder. Since the discovery of
antidepressant (AD) properties of the imipramine and then after of other tricyclic compounds …

Endogenous opiates and behavior: 2013

RJ Bodnar - Peptides, 2014 - Elsevier
This paper is the thirty-sixth consecutive installment of the annual review of research
concerning the endogenous opioid system. It summarizes papers published during 2013 …

Co-occurrence of anxiety and depressive-like behaviors following adolescent social isolation in male mice; possible role of nitrergic system

S Amiri, A Haj-Mirzaian, M Rahimi-Balaei, A Razmi… - Physiology & …, 2015 - Elsevier
Approximately more than 50% of patients with depression have the co-occurrence of
anxiety, which complicates the treatment of disease. Recently, social isolation stress (SIS) …

Elevated level of nitric oxide mediates the anti-depressant effect of rubidium chloride in mice

N Kordjazy, A Haj-Mirzaian, S Amiri… - European journal of …, 2015 - Elsevier
Rubidium has been used to treat psychiatric conditions including depression. We examined
the antidepressant activity of rubidium chloride (RbCl) in male mice and the possible …

Blockade of NMDA receptors reverses the depressant, but not anxiogenic effect of adolescence social isolation in mice

A Haj-Mirzaian, S Amiri, N Kordjazy… - European journal of …, 2015 - Elsevier
Early life social isolation stress (SIS), a well-known chronic stress paradigm, is contributed to
a number of pathophysiological and neurochemical changes including depression and …

Evidence for the involvement of NMDA receptors in the antidepressant-like effect of nicotine in mouse forced swimming and tail suspension tests

A Haj-Mirzaian, N Kordjazy, A Haj-Mirzaian… - …, 2015 - Springer
Rationale The antidepressant action of acute nicotine administration in clinical and animal
studies is well recognized. But the underlying mechanism for this effect has not been …

Opioid/NMDA receptors blockade reverses the depressant-like behavior of foot shock stress in the mouse forced swimming test

A Haj-Mirzaian, S Ostadhadi, N Kordjazy… - European journal of …, 2014 - Elsevier
Opioid and glutamatergic receptors have a key role in depression following stress. In this
study, we assessed opioid and glutamatergic receptors interaction with the depressant-like …

Involvement of the nitrergic system in the proconvulsant effect of social isolation stress in male mice

S Amiri, A Shirzadian, A Haj-Mirzaian, M Imran-Khan… - Epilepsy & Behavior, 2014 - Elsevier
Social isolation stress (SIS) in adolescence is accompanied by neurobehavioral
disturbances and pathophysiological changes in certain regions of the CNS such as the …

Possible involvement of nitrergic and opioidergic systems in the modulatory effect of acute chloroquine treatment on pentylenetetrazol induced convulsions in mice

M Hassanipour, A Shirzadian, MMA Boojar… - Brain research …, 2016 - Elsevier
Chloroquine has long been used for the treatment of malaria and rheumatological disorders.
Accumulating evidence suggests potential use of chloroquine as a neuroprotective agent …

Opioidergic and nitrergic systems mediate the anticonvulsant effect of mefloquine and chloroquine on seizures induced by pentylenetetrazol and maximal …

S Boroujeni, S Solaimanian, R Jafari… - Acta Neurobiologiae …, 2022 - ane.pl
This study was designed to investigate the involvement of opioidergic/nitrergic systems in
the anticonvulsant effect of mefloquine, compared with chloroquine, in mice. Seizures were …