Developmental toxicity assessment of neonicotinoids and organophosphate esters with a human embryonic stem cell-and metabolism-based fast-screening model

S Zhang, M Zhao, S Li, R Yang, N Yin… - Journal of Environmental …, 2024 - Elsevier
In recent years, neonicotinoids (NEOs) and organophosphate esters (OPEs) have been
widely used as substitutes for traditional pesticides and brominated flame-retardants …

[HTML][HTML] Toxicity of pesticides widely applied on soybean cultivation: synergistic effects of fipronil, glyphosate and imidacloprid in HepG2 cells

FM Conte, LV Cestonaro, YV Piton, N Guimarães… - Toxicology in Vitro, 2022 - Elsevier
The transgenic soy monoculture demands supplementation with pesticides. The aim of this
study was to evaluate the individual and mixture effects of fipronil, glyphosate and …

Non-acute exposure of neonicotinoids, health risk assessment, and evidence integration: a systematic review

I Benchikh, K Ziani, A Gonzalez Mateos… - Critical Reviews in …, 2024 - Taylor & Francis
Neonicotinoid pesticides are utilized against an extensive range of insects. A growing body
of evidence supports that these neuro-active insecticides are classified as toxicants in …

Effects of imidacloprid on viability and increase of reactive oxygen and nitrogen species in HepG2 cell line

ARJS Guimarães, PFV Bizerra… - Toxicology …, 2022 - Taylor & Francis
Imidacloprid (IMD) is a neonicotinoid insecticide used in large quantities worldwide in both
veterinary and agronomic applications. Several studies have shown adverse effects of IMD …

[HTML][HTML] The metabolic and toxic acute effects of phloretin in the rat liver

FSI Da Silva, PFV Bizerra, MS Mito… - Chemico-Biological …, 2022 - Elsevier
The current study sought to evaluate the acute effects of phloretin (PH) on metabolic
pathways involved in the maintenance of glycemia, specifically gluconeogenesis and …

Thymol's modulation of cellular macromolecules, oxidative stress, DNA damage, and NF-kB/caspase-3 signaling in the liver of imidacloprid-exposed rats

FE Abdelgawad, GI Abd El-Rahman, A Behairy… - Environmental …, 2024 - Elsevier
We evaluated whether thymol (THY)(30 mg/kg b. wt) could relieve the adverse effects of the
neonicotinoid insecticide imidacloprid (IMD)(22.5 mg/kg b. wt) on the liver in a 56-day oral …

Temperature-dependent in vitro hepatocytotoxicity of insecticides in bats

M Nemcova, J Zukal, V Seidlova, S Bednarikova… - Environmental …, 2024 - Elsevier
Heterothermic insectivorous bats are supposed to experience differential adverse effects of
insecticidal pollutants depending on their seasonal and/or daily variation of metabolic and …

The harmful acute effects of clomipramine in the rat liver: impairments in mitochondrial bioenergetics

PFV Bizerra, FSI da Silva, EH Gilglioni, LF Nanami… - Toxicology Letters, 2023 - Elsevier
Clomipramine, a tricyclic antidepressant used to treat depression and obsessive-compulsive
disorder, has been linked to a few cases of acute hepatotoxicity. It is also recognized as a …

[HTML][HTML] The photosensitiser azure A disrupts mitochondrial bioenergetics through intrinsic and photodynamic effects

BTL de Souza, EM Klosowski, MS Mito, RP Constantin… - Toxicology, 2021 - Elsevier
Azure A (AA) is a cationic molecule of the class of phenothiazines that has been applied in
vitro as a photosensitising agent in photodynamic antimicrobial chemotherapy. It is a di …

Efekti ekstrakata biljne vrste Viscum album L. na toksičnost insekticida hlorpirifosa i imidakloprida kod različitih eksperimentalnih model sistema

MD Milošević - Универзитет у Крагујевцу, 2023 - nardus.mpn.gov.rs
Hlorpirifos (CPF) i imidakloprid (IMI) su insekticidi koji se široko upotrebljavaju u zaštiti
biljaka. Viscum album L. je semiparazitska biljka koja ima tradicionalnu upotrebu u lečenju …