Resveratrol (3, 5, 4′-trihydroxystilbene; RSV) is a natural nonflavonoid polyphenol present
in many species of plants, particularly in grapes, blueberries, and peanuts. Several in vitro …

Cancer is a prevalent cause of mortality around the world. Aberrated activation of Janus
kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway …

The concept of a scaffold concerns many aspects at different steps on the drug development
path. In medicinal chemistry, the choice of relevant “drug-likeness” scaffold is a starting point …

Globally, breast cancer is the most frequently diagnosed cancer among women. The major
unresolved problems with metastatic breast cancer is recurrence after receiving objective …

Breast cancer is one of the leading causes of cancer-related morbidity and mortality among
women worldwide. Phytoestrogens, plant-derived polyphenols that structurally and …

Resveratrol, a natural phytoalexin, exhibits a remarkable range of biological activities, such
as anticancer, cardioprotective, neuroprotective and antioxidant properties. However, the …

Stilbene is an abundant structural scaffold in nature, and stilbene‐based compounds have
been widely reported for their biological activity. Notably,(E)‐resveratrol and its natural …

Phytochemicals are an important part of traditional medicine and have been investigated in
detail for possible inclusion in modern medicine as well. These compounds often serve as …

The Wittig reaction involving direct olefination of triphenylphosphonium ylides (Ph3P CHR)
with aldehydes is arguably the most often used method for alkene synthesis, but in general it …

The outcome of producing apoptotic defects in cancer cells is the primary obstacle that limits
the therapeutic efficacy of anticancer agents, and hence the development of novel agents …