Organocatalytic reactions enabled by N-heterocyclic carbenes

DM Flanigan, F Romanov-Michailidis, NA White… - Chemical …, 2015 - ACS Publications
Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes | Chemical Reviews ACS
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NHC-catalyzed generation of α, β-unsaturated acylazoliums for the enantioselective synthesis of heterocycles and carbocycles

S Mondal, SR Yetra, S Mukherjee… - Accounts of Chemical …, 2019 - ACS Publications
Conspectus This Account is aimed at highlighting the recent developments in the N-
heterocyclic carbene (NHC)-catalyzed generation of α, β-unsaturated acylazolium …

N‐Heterocyclic Carbene Organocatalysis: Activation Modes and Typical Reactive Intermediates

X Chen, H Wang, Z Jin, YR Chi - Chinese Journal of Chemistry, 2020 - Wiley Online Library
N‐Heterocyclic carbene (NHC) organocatalysis has been developed as an important
approach in modern organic synthesis. Versatile activation modes within NHC …

Isatins as privileged molecules in design and synthesis of spiro-fused cyclic frameworks

GS Singh, ZY Desta - Chemical Reviews, 2012 - ACS Publications
1. INTRODUCTION Indoline-2, 3-dione or indole-1H-2, 3-dione (Figure 1), commonly known
as isatin, is a well-known natural product found in plants of genus Isatis and in Couropita …

A continuing challenge: N-heterocyclic carbene-catalyzed syntheses of γ-butyrolactones

KJR Murauski, AA Jaworski, KA Scheidt - Chemical Society Reviews, 2018 - pubs.rsc.org
Catalytic, stereoselective N-heterocyclic carbene-catalyzed reactions facilitate efficient
construction of many different heterocyclic compounds, such as the enantioenriched 5 …

Recent advances in asymmetric Organocatalytic construction of 3, 3′‐Spirocyclic Oxindoles

L Hong, R Wang - Advanced Synthesis & Catalysis, 2013 - Wiley Online Library
The asymmetric organocatalysis is definitely one of the most powerful and versatile tools for
the rapid construction of various spirocyclic oxindoles. In the past few years, a number of …

Catalytic asymmetric synthesis of butenolides and butyrolactones

B Mao, M Fañanás-Mastral, BL Feringa - Chemical reviews, 2017 - ACS Publications
γ-Butenolides, γ-butyrolactones, and derivatives, especially in enantiomerically pure form,
constitute the structural core of numerous natural products which display an impressive …

Organocatalysis by N-heterocyclic carbenes

D Enders, O Niemeier, A Henseler - Chemical Reviews, 2007 - ACS Publications
In the investigation of efficient chemical transformations, the carbon-carbon bond-forming
reactions play an outstanding role. In this context, organocatalytic processes have achieved …

Recent advances in employing homoenolates generated by N-heterocyclic carbene (NHC) catalysis in carbon–carbon bond-forming reactions

RS Menon, AT Biju, V Nair - Chemical Society Reviews, 2015 - pubs.rsc.org
The use of NHCs for generating homoenolate species has gained widespread popularity in
recent years. A number of highly stereoselective processes of NHC-homoenolates have …

N‐heterocyclic carbenes as organocatalysts

N Marion, S Díez‐González… - Angewandte Chemie …, 2007 - Wiley Online Library
Organocatalyzed reactions represent an attractive alternative to metal‐catalyzed processes
notably because of their lower cost and benign environmental impact in comparison to …