During starvation, fasting, or a diet containing little digestible carbohydrates, the circulating
insulin levels are decreased. This promotes lipolysis, and the breakdown of fat becomes the …

Background Cancer is one of the greatest public health challenges worldwide, and we still
lack complementary approaches to significantly enhance the efficacy of standard anticancer …

The prevalence of obesity, measured by body mass index, has risen to unacceptable levels
in both men and women in the United States and worldwide with resultant hazardous health …

Very-low-carbohydrate ketogenic diets have been long been used to reduce seizure
frequency and more recently have been promoted for a variety of health conditions …

Importance Dietary modification remains key to successful weight loss. Yet, no one dietary
strategy is consistently superior to others for the general population. Previous research …

Robert is a 47-year-old patient who initially weighed 120 kilograms. He lost 40 kilograms 3
years ago by carefully following your guidance to decrease his caloric intake to 1500 …

Numerous combinations of diets and pharmacological agents, including lifestyle changes,
have been launched to treat obesity. There are still ambiguities regarding the efficacies of …

The evolution of dietary guidelines from isolated nutrients to broader dietary pattern
recommendations results from growing knowledge of the synergy between nutrients and …

Methods We conducted an open-label, non-randomized, controlled, before-and-after 1-year
study of this continuous care intervention (CCI) and usual care (UC). Primary outcomes were …

Importance Alternate-day fasting has become increasingly popular, yet, to date, no long-term
randomized clinical trials have evaluated its efficacy. Objective To compare the effects of …