Disparities at presentation, diagnosis, treatment, and survival in African American men, affected by prostate cancer

G Chornokur, K Dalton, ME Borysova, NB Kumar - The Prostate, 2011 - Wiley Online Library
BACKGROUND Prostate cancer (PCa) remains the most common malignancy and the
second leading cause of cancer death among men in the United States. PCa exhibits the …

The pathologic role of toll-like receptor 4 in prostate cancer

T Ou, M Lilly, W Jiang - Frontiers in immunology, 2018 - frontiersin.org
Toll-like receptor (TLR) 4 is expressed on normal and malignant prostate epithelial cells.
The TLR4 and its downstream signaling pathways mediate innate immune responses in the …

Molecular classification of prostate cancer using curated expression signatures

EK Markert, H Mizuno, A Vazquez… - Proceedings of the …, 2011 - National Acad Sciences
High Gleason score is currently the best prognostic indicator for poor prognosis in prostate
cancer. However, a significant number of patients with low Gleason scores develop …

Geographic distribution of racial differences in prostate cancer mortality

SA Fletcher, M Marchese, AP Cole, BA Mahal… - JAMA network …, 2020 - jamanetwork.com
Importance While racial disparities in prostate cancer mortality are well documented, it is not
well known how these disparities vary geographically within the US. Objective To …

Emerging role of exosomes in the pathology of chronic obstructive pulmonary diseases; destructive and therapeutic properties

H Rajabi, N Konyalilar, S Erkan, D Mortazavi… - Stem Cell Research & …, 2022 - Springer
Chronic obstructive pulmonary disease (COPD) is known as the third leading cause of
human death globally. Enhanced chronic inflammation and pathological remodeling are the …

Methylome-wide sequencing detects DNA hypermethylation distinguishing indolent from aggressive prostate cancer

JM Bhasin, BH Lee, L Matkin, MG Taylor, B Hu, Y Xu… - Cell reports, 2015 - cell.com
A critical need in understanding the biology of prostate cancer is characterizing the
molecular differences between indolent and aggressive cases. Because DNA methylation …

Biomarkers for acute and chronic graft versus host disease: state of the art

L Giaccone, DG Faraci, S Butera, G Lia… - Expert Review of …, 2021 - Taylor & Francis
Introduction Despite significant advances in treatment and prevention, graft-versus-host
disease (GVHD) still represents the main cause of morbidity and mortality after allogeneic …

Association of TLR2, TLR3, TLR4 and CD14 genes polymorphisms with oral cancer risk and survival

K Zeljic, G Supic, N Jovic, R Kozomara… - Oral …, 2014 - Wiley Online Library
Objectives The aim of this study is to investigate association between polymorphisms in TLR
2, TLR 3, TLR 4 and CD 14 genes or their haplotypes with oral squamous cell carcinomas …

[HTML][HTML] LBP and CD14 polymorphisms correlate with increased colorectal carcinoma risk in Han Chinese

R Chen, FK Luo, YL Wang, JL Tang… - World Journal of …, 2011 - ncbi.nlm.nih.gov
AIM: To explore the associations of polymorphisms of lipopolysaccharide binding protein
(LBP), cluster of differentiation 14 (CD14), toll-like receptor 4 (TLR-4), interleukin-6 (IL-6) …

Increased Plasmatic Levels of Exosomes Are Significantly Related to Relapse Rate in Patients with Oral Squamous Cell Carcinoma: A Cohort Study

S Rodríguez-Zorrilla, AI Lorenzo-Pouso, S Fais… - Cancers, 2023 - mdpi.com
Simple Summary This study investigates the potential of exosomal profiles as a tool for early
detection of relapse and long-term outcomes in oral squamous cell carcinoma (OSCC) …