Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics,
including altered iron homeostasis, reduced defense against oxidative stress, and abnormal …

Ferroptosis is a non-apoptotic cell death mechanism characterized by iron-dependent
membrane lipid peroxidation. Here, we review what is known about the cellular mechanisms …

Lipid droplets are dynamic organelles that store neutral lipids, serve the metabolic needs of
cells, and sequester lipids to prevent lipotoxicity and membrane damage. Here we review …

Cellular quality control systems sense and mediate homeostatic responses to prevent the
buildup of aberrant macromolecules, which arise from errors during biosynthesis, damage …

Ferroptosis is a non-apoptotic form of cell death that can be triggered by inhibiting the
system xc− cystine/glutamate antiporter or the phospholipid hydroperoxidase glutathione …

How cells coordinate cell cycling with cell survival and death remains incompletely
understood. Here, we show that cell cycle arrest has a potent suppressive effect on …

Background Glioma exhibit heterogeneous susceptibility for targeted ferroptosis. How
circRNAs alterations in glioma promote iron metabolism and ferroptosis defense remains …

Ferroptosis is a distinct lipid peroxidation-dependent form of necrotic cell death. This
process has been increasingly contemplated as a new target for cancer therapy because of …

Ferroptosis is associated with excessive lipid peroxidation (LPO) accumulation, followed by
membrane fragmentation. Although lipid metabolism is essential for regulating ferroptosis …

Radiotherapy is pivotal in treating head and neck cancers including nasopharyngeal,
tongue, hypopharyngeal, larynx, maxillary sinus, parotid gland, and oral cancers. It holds the …