[HTML][HTML] Liver fibrosis in non-alcoholic fatty liver disease: from liver biopsy to non-invasive biomarkers in diagnosis and treatment

LJM Heyens, D Busschots, GH Koek, G Robaeys… - Frontiers in …, 2021 - frontiersin.org
An increasing percentage of people have or are at risk to develop non-alcoholic fatty liver
disease (NAFLD) worldwide. NAFLD comprises different stadia going from isolated steatosis …

[HTML][HTML] The role of insulin resistance and diabetes in nonalcoholic fatty liver disease

H Fujii, N Kawada… - International journal of …, 2020 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) consists of the entire spectrum of fatty liver disease
in patients without significant alcohol consumption, ranging from nonalcoholic fatty liver …

[HTML][HTML] Role of diet and gut microbiota on colorectal cancer immunomodulation

CV De Almeida, MR de Camargo, E Russo… - World journal of …, 2019 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most commonly diagnosed cancers, and it is
characterized by genetic and epigenetic alterations, as well as by inflammatory cell …

[HTML][HTML] Current status, problems, and perspectives of non-alcoholic fatty liver disease research

N Tanaka, T Kimura, N Fujimori, T Nagaya… - World journal of …, 2019 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is a major chronic liver disease that can lead to
liver cirrhosis, liver cancer, and ultimately death. NAFLD is pathologically classified as non …

[HTML][HTML] Hepatic stellate cells: dictating outcome in nonalcoholic fatty liver disease

L Wiering, P Subramanian, L Hammerich - Cellular and Molecular …, 2023 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is a fast growing, chronic liver disease affecting∼
25% of the global population. Nonalcoholic fatty liver disease severity ranges from the less …

[HTML][HTML] SWOT analysis of noninvasive tests for diagnosing NAFLD with severe fibrosis: an expert review by the JANIT Forum

Y Kamada, T Nakamura, S Isobe, K Hosono… - Journal of …, 2023 - Springer
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease.
Nonalcoholic steatohepatitis (NASH) is an advanced form of NAFLD can progress to liver …

[HTML][HTML] Pemafibrate improves liver dysfunction and non-invasive surrogates for liver fibrosis in patients with non-alcoholic fatty liver disease with hypertriglyceridemia …

A Morishita, K Oura, K Takuma, M Nakahara… - Hepatology …, 2023 - Springer
Background This retrospective, multicenter study evaluated the effect of pemafibrate
treatment on liver function and fibrosis by liver function tests (LFTs) and various fibrotic …

[HTML][HTML] Inhibition of autotaxin alleviates pathological features of hepatic encephalopathy at the level of gut–liver–brain axis: an experimental and bioinformatic study

A Sepehrinezhad, A Shahbazi, MT Joghataei… - Cell death & …, 2023 - nature.com
There is accumulating evidence that the circulatory levels of autotaxin (ATX) and
lysophosphatidic acid (LPA) are increased in patients with severe liver disease. However …

[HTML][HTML] FIB-4 first in the diagnostic algorithm of metabolic-dysfunction-associated fatty liver disease in the era of the global metabodemic

Y Sumida, M Yoneda, K Tokushige, M Kawanaka… - Life, 2021 - mdpi.com
The prevalence of obesity or metabolic syndrome is increasing worldwide (globally
metabodemic). Approximately 25% of the adult general population is suffering from …

[HTML][HTML] Cholestasis-associated pruritus and its pruritogens

JAGM Langedijk, UH Beuers… - Frontiers in Medicine, 2021 - frontiersin.org
Pruritus is a debilitating symptom of various cholestatic disorders, including primary biliary
cholangitis (PBC), primary sclerosing cholangitis (PSC) and inherited progressive familial …