Polyphenols constitute an important group of natural products that are traditionally
associated with a wide range of bioactivities. These are usually found in low concentrations …

Breast cancer (BC) is one of the most common causes of cancer in the world and the second
leading cause of cancer deaths among women. Mortality is associated mainly with the …

Smoking has a profound impact on tumor immunity, and nicotine, which is the major
addictive component of smoke, is known to promote tumor progression despite being a non …

This Opinion article discusses emerging evidence of direct contributions of nicotine to
cancer onset and growth. The list of cancers reportedly connected to nicotine is expanding …

The spread of cancer cells to distant organs represents a major clinical challenge in the
treatment of cancer. Epithelial–mesenchymal transition (EMT) has emerged as a key …

Tobacco smoke contains multiple classes of established carcinogens including benzo (a)
pyrenes, polycyclic aromatic hydrocarbons, and tobacco-specific nitrosamines. Most of these …

Background Cigarette smoking contributes to lung remodelling in chronic obstructive
pulmonary disease (COPD). As part of remodelling, peribronchiolar fibrosis is observed in …

The epithelial to mesenchymal transition or EMT has become one of the most exciting fields
in cancer research. Nevertheless, its relevance in tumor biology and the metastatic process …

Background Lung cancer is the leading cause of cancer related deaths and its incidence is
highly correlated with cigarette smoking. Nicotine, the addictive component of tobacco …

Epidemiological and clinical studies over the past two decades have provided strong
evidence that genetic elements interacting with environmental components can individually …