Anchorage-independent survival of cancer cells is associated with metastasis as it enables
cells to travel to secondary target sites. Tissue integrity is generally maintained by …

The extracellular matrix (ECM) is an integral component of all organs and plays a pivotal
role in tissue homeostasis and repair. While the ECM was long thought to mostly have …

Background Glioblastoma (GBM) is the most prominent and aggressive primary brain tumor
in adults. Anoikis is a specific form of programmed cell death that plays a key role in tumor …

Low-grade glioma (LGG) is a highly aggressive disease in the skull. On the other hand,
anoikis, a specific form of cell death induced by the loss of cell contact with the extracellular …

Mounting evidence suggests that platelets play an essential role in cancer metastasis. The
interactions between platelets and circulating tumor cells (CTCs) promote cancer …

Metastatic cancer cells can develop anoikis resistance in the absence of substrate
attachment and survive to fight tumors. Anoikis is mediated by endogenous mitochondria …

Melanoma as the most major skin malignancy has attracted much attention, so far. Although
a successful therapeutic strategy requires an accurate understanding of the precise …

The main role of platelets is to control bleeding and repair vascular damage via thrombosis.
They have also been implicated to promote tumor metastasis through platelet-tumor cell …

Background In addition to their pivotal roles in coagulation and thrombosis, platelets are
crucial in tumor progression, with plenty of clinical and experimental data demonstrating that …

The fate of a viral infection in the host begins with various types of cellular responses, such
as abortive, productive, latent, and destructive infections. Apoptosis, necroptosis, and …