Statins, which are widely used to treat hypercholesterolemia, have anti-inflammatory and
anti-oxidant effects. These are thought to be responsible for the potential effects of statins on …

The growing number of publications concerning postoperative cognitive decline (POCD)
after cardiac surgery is indicative of the health-related and economic-related importance of …

In a subset of patients, chronic exposure to stress is an etiological risk factor for
neuroinflammation and depression. Neuroinflammation affects up to 27% of patients with …

Introduction: Saffron (Crocus sativus L.) has demonstrated antidepressant effects in clinical
studies and extensive anxiolytic effects in experimental animal models. Methods: 66 patients …

Background In epidemiological studies, statins appear to benefit mood, and there are now
some randomized controlled trials examining the efficacy of statins. However, the role of …

Background: Depression is a leading cause of disability, burdened by high levels of non-
response to conventional antidepressants. Novel therapeutic strategies targeting non …

Introduction: Postpartum depression is a common mental health problem that is associated
with maternal suffering. The aim of this double-blind clinical trial was to compare safety and …

Background The burden of depressive disorder is large and new treatment approaches are
required. Repurposing widely available drugs such as statins may be a time-and cost …

Background Clinical trials of the effects of statins in people with and without depressive
symptoms at baseline have yielded conflicting results with studies reporting both an …

Statins are widely accepted as first-choice agents for the prevention of lipid-related
cardiovascular diseases. These drugs have both anti-inflammatory and anti-oxidant …