Circular RNAs and complex diseases: from experimental results to computational models

CC Wang, CD Han, Q Zhao, X Chen - Briefings in bioinformatics, 2021 - academic.oup.com
Circular RNAs (circRNAs) are a class of single-stranded, covalently closed RNA molecules
with a variety of biological functions. Studies have shown that circRNAs are involved in a …

Deep learning models for disease-associated circRNA prediction: a review

Y Chen, J Wang, C Wang, M Liu… - Briefings in …, 2022 - academic.oup.com
Emerging evidence indicates that circular RNAs (circRNAs) can provide new insights and
potential therapeutic targets for disease diagnosis and treatment. However, traditional …

[HTML][HTML] Network learning for biomarker discovery

Y Ding, M Fu, P Luo, FX Wu - International Journal of Network Dynamics …, 2023 - sciltp.com
Everything is connected and thus networks are instrumental in not only modeling complex
systems with many components, but also accommodating knowledge about their …

MPCLCDA: predicting circRNA–disease associations by using automatically selected meta-path and contrastive learning

W Liu, T Tang, X Lu, X Fu, Y Yang… - Briefings in …, 2023 - academic.oup.com
Circular RNA (circRNA) is closely associated with human diseases. Accordingly, identifying
the associations between human diseases and circRNA can help in disease prevention …

A comprehensive survey on computational methods of non-coding RNA and disease association prediction

X Lei, TB Mudiyanselage, Y Zhang… - Briefings in …, 2021 - academic.oup.com
The studies on relationships between non-coding RNAs and diseases are widely carried out
in recent years. A large number of experimental methods and technologies of producing …

IGNSCDA: predicting CircRNA-disease associations based on improved graph convolutional network and negative sampling

W Lan, Y Dong, Q Chen, J Liu, J Wang… - IEEE/ACM …, 2021 - ieeexplore.ieee.org
Accumulating evidences have shown that circRNA plays an important role in human
diseases. It can be used as potential biomarker for diagnose and treatment of disease …

Predicting CircRNA disease associations using novel node classification and link prediction models on graph convolutional networks

TB Mudiyanselage, X Lei, N Senanayake, Y Zhang… - Methods, 2022 - Elsevier
Accumulated studies have discovered that circular RNAs (CircRNAs) are closely related to
many complex human diseases. Due to this close relationship, CircRNAs can be used as …

Benchmarking of computational methods for predicting circRNA-disease associations

W Lan, Y Dong, H Zhang, C Li, Q Chen… - Briefings in …, 2023 - academic.oup.com
Accumulating evidences demonstrate that circular RNA (circRNA) plays an important role in
human diseases. Identification of circRNA-disease associations can help for the diagnosis of …

THGNCDA: circRNA–disease association prediction based on triple heterogeneous graph network

Y Guo, M Yi - Briefings in Functional Genomics, 2023 - academic.oup.com
Circular RNAs (circRNAs) are a class of noncoding RNA molecules featuring a closed
circular structure. They have been proved to play a significant role in the reduction of many …

[HTML][HTML] Prioritizing CircRNA–disease associations with convolutional neural network based on multiple similarity feature fusion

C Fan, X Lei, Y Pan - Frontiers in genetics, 2020 - frontiersin.org
Accumulating evidence shows that circular RNAs (circRNAs) have significant roles in human
health and in the occurrence and development of diseases. Biological researchers have …