Simple Summary Microtubules (MTs) are highly conserved proteins present in all eukaryotic
organisms. They form the cell cytoskeleton, and its function is essential for a large number of …

The centriole is an ancient microtubule-based organelle with a conserved nine-fold
symmetry. Centrioles form the core of centrosomes, which organize the interphase …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Since the discovery of leucine-rich repeat kinase 2 (LRRK2) as a protein that is likely central
to the aetiology of Parkinson's disease, a considerable amount of work has gone into …

Different blood flow patterns in the arteries can alter the adaptive phenotype of vascular
endothelial cells (ECs), thereby affecting the functions of ECs and are directly associated …

Heterotopic ossification (HO) is defined as the occurrence of extraskeletal bone in soft
tissue. Although this pathological osteogenesis process involves the participation of …

Ciliopathies comprise a group of complex disorders, with involvement of the majority of
organs and systems. In total,> 180 causal genes have been identified and, in addition to …

The respiratory epithelium is intimately associated with the pathophysiologies of highly
infectious viral contagions and chronic illnesses such as chronic obstructive pulmonary …

Bardet-Biedl syndrome (BBS) is a currently incurable ciliopathy caused by the failure to
correctly establish or maintain cilia-dependent signaling pathways. Eight proteins …

Mechanical loading is essential for chondrocyte health. Chondrocytes can sense and
respond to various extracellular mechanical signals through an integrated set of …