Biomarkers of HFpEF: natriuretic peptides, high-sensitivity troponins and beyond

P Morfino, A Aimo, V Castiglione, G Vergaro… - Journal of …, 2022 - mdpi.com
Heart failure (HF) is a significant cause of morbidity and mortality worldwide. HF with
preserved ejection fraction (HFpEF) is a complex syndrome, often participated by several …

[HTML][HTML] Role of cardiac troponin levels in acute heart failure

N Wettersten, A Maisel - Cardiac failure review, 2015 - ncbi.nlm.nih.gov
Cardiac troponin (cTn) is the primary biomarker for the diagnosis of myocardial necrosis in
an acute coronary syndrome (ACS). cTn levels can also be elevated in many other …

Circulating biomarkers of distinct pathophysiological pathways in heart failure with preserved vs. reduced left ventricular ejection fraction

S Sanders‐van Wijk, V van Empel… - European journal of …, 2015 - Wiley Online Library
Aims The aim of this study was to evaluate whether biomarkers reflecting pathophysiological
pathways are different between heart failure with preserved (HFpEF) and reduced ejection …

Elevation in high-sensitivity troponin T in heart failure and preserved ejection fraction and influence of treatment with the angiotensin receptor neprilysin inhibitor …

PS Jhund, BL Claggett, AA Voors, MR Zile… - Circulation: Heart …, 2014 - Am Heart Assoc
Background—Elevated high-sensitivity troponin is associated with increasing disease
severity in patients with stable heart failure with reduced ejection fraction, but less is known …

Cardiac troponin I and risk of cardiac events in patients with heart failure and preserved ejection fraction

PL Myhre, E O'Meara, BL Claggett… - Circulation: Heart …, 2018 - Am Heart Assoc
Background: Levels of cTn (cardiac troponin) are frequently elevated in patients with heart
failure (HF) and reduced ejection fraction (EF) and correlate with the risk for mortality …

Plasma cardiac troponin I concentration and cardiac death in cats with hypertrophic cardiomyopathy

K Borgeat, K Sherwood, JR Payne… - Journal of Veterinary …, 2014 - Wiley Online Library
Background The use of cardiac biomarkers to assist in the diagnosis of occult and
symptomatic hypertrophic cardiomyopathy (HCM) in cats has been established. There is …

Factors associated with and prognostic implications of cardiac troponin elevation in decompensated heart failure with preserved ejection fraction: findings from the …

A Pandey, H Golwala, S Sheng, AD DeVore… - JAMA …, 2017 - jamanetwork.com
Importance Elevated levels of cardiac troponins are associated with adverse clinical
outcomes among patients with heart failure (HF) and reduced ejection fraction. However, the …

[HTML][HTML] Prognostic markers of acute decompensated heart failure: the emerging roles of cardiac biomarkers and prognostic scores

A Cohen-Solal, S Laribi, S Ishihara, G Vergaro… - Archives of …, 2015 - Elsevier
Rapidly assessing outcome in patients with acute decompensated heart failure is important
but prognostic factors may differ from those used routinely for stable chronic heart failure …

Troponins in heart failure

T Omland, H Røsjø, E Giannitsis, S Agewall - Clinica chimica acta, 2015 - Elsevier
The signs and symptoms of heart failure are frequently unspecific and correlate poorly with
objective indices of cardiac function. Objective assessment of cardiac function by …

Rationale for and design of the TRUE‐AHF trial: the effects of ularitide on the short‐term clinical course and long‐term mortality of patients with acute heart failure

M Packer, R Holcomb, WT Abraham… - European journal of …, 2017 - Wiley Online Library
The TRUE‐AHF is a randomized, double‐blind, parallel‐group, placebo‐controlled trial
which is evaluating the effects of a 48‐h infusion of ularitide (15 ng/kg/min) on the short‐and …