In vitro allosteric transcription factor-based biosensing

S Li, Z Li, GY Tan, Z Xin, W Wang - Trends in Biotechnology, 2023 - cell.com
A biosensor is an analytical device that converts a biological response into a measurable
output signal. Bacterial allosteric transcription factors (aTFs) have been utilized as a novel …

Affinity biosensors developed with quantum dots in microfluidic systems

S Şahin, C Ünlü, L Trabzon - Emergent Materials, 2021 - Springer
Quantum dots (QDs) are synthetic semiconductor nanocrystals with unique optical and
electronic properties due to their size (2–10 nm) such as high molar absorption coefficient …

Hydrogel-Embedded Quantum Dot–Transcription Factor Sensors for Quantitative Progesterone Detection

M Chen, C Grazon, P Sensharma… - … Applied Materials & …, 2020 - ACS Publications
Immobilization of biosensors in or on a functional material is critical for subsequent device
development and translation to wearable technology. Here, we present the development …

Transcription Factor Based Small‐Molecule Sensing with a Rapid Cell Phone Enabled Fluorescent Bead Assay

M Chern, PM Garden, RC Baer… - Angewandte Chemie …, 2020 - Wiley Online Library
Recently, allosteric transcription factors (TFs) were identified as a novel class of
biorecognition elements for in vitro sensing, whereby an indicator of the differential binding …

Double-Stranded DNA Immobilized in Lying-Flat and Upright Orientation on a PNIPAm-Coated Surface: A Theoretical Study

C Feng, X Liu, Y Sun, C Ren - ACS Macro Letters, 2024 - ACS Publications
Surface-immobilized double-stranded DNA (dsDNA) in upright orientation plays an
important role in optimizing and understanding DNA-based nanosensors and nanodevices …

Advances in the use of nanomaterials for nucleic acid detection in point-of-care testing devices: A review

Z He, C Liu, Z Li, Z Chu, X Chen, X Chen… - … in Bioengineering and …, 2022 - frontiersin.org
The outbreak of the coronavirus (COVID-19) has heightened awareness of the importance of
quick and easy testing. The convenience, speed, and timely results from point-of-care testing …

Based Progesterone Sensor Using an Allosteric Transcription Factor

M Zamani, J Dupaty, RC Baer, U Kuzmanovic, A Fan… - ACS …, 2022 - ACS Publications
Progesterone monitoring is an essential component of in vitro fertilization treatments and
reproductive management of dairy cows. Gold-standard biosensors for progesterone …

Elementary processes of DNA surface hybridization resolved by single-molecule kinetics: implication for macroscopic device performance

T Harashima, Y Hasegawa, S Kaneko, Y Jono… - Chemical …, 2021 - pubs.rsc.org
Direct monitoring of single-molecule reactions has recently become a promising means of
mechanistic investigation. However, the resolution of reaction pathways from single …

Quantum dots for sensing applications

S Şahin, Ö Ergüder, L Trabzon, C Ünlü - Fundamentals of Sensor …, 2023 - Elsevier
Synthetic nanoscale semiconductor nanocrystals, aka quantum dots (QDs), are excellent
fluorophore candidates for sensing technology due to their spectacular optical and …

Affordable technologies for point-of-care diagnostics

M Zamani - 2021 - search.proquest.com
Affordable, point-of-care diagnostics are needed for disease monitoring in low-resource
settings (LRS). Gold-standard laboratory tests require expensive benchtop equipment …