[HTML][HTML] Cough hypersensitivity and chronic cough
Chronic cough is globally prevalent across all age groups. This disorder is challenging to
treat because many pulmonary and extrapulmonary conditions can present with chronic …
treat because many pulmonary and extrapulmonary conditions can present with chronic …
Adult‐onset eosinophilic airway diseases
K Asano, S Ueki, M Tamari, Y Imoto, S Fujieda… - Allergy, 2020 - Wiley Online Library
Eosinophilic airway inflammation is one of the cardinal features of allergic airway diseases
such as atopic asthma and allergic rhinitis. These childhood‐onset conditions are mediated …
such as atopic asthma and allergic rhinitis. These childhood‐onset conditions are mediated …
Eosinophil extracellular traps drive asthma progression through neuro-immune signals
Y Lu, Y Huang, J Li, J Huang, L Zhang, J Feng, J Li… - Nature Cell …, 2021 - nature.com
Eosinophilic inflammation is a feature of allergic asthma. Despite mounting evidence
showing that chromatin filaments released from neutrophils mediate various diseases, the …
showing that chromatin filaments released from neutrophils mediate various diseases, the …
[HTML][HTML] A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment
A Balestrini, V Joseph, M Dourado, RM Reese… - Journal of Experimental …, 2021 - rupress.org
Despite the development of effective therapies, a substantial proportion of asthmatics
continue to have uncontrolled symptoms, airflow limitation, and exacerbations. Transient …
continue to have uncontrolled symptoms, airflow limitation, and exacerbations. Transient …
Eosinophils are part of the granulocyte response in tuberculosis and promote host resistance in mice
AC Bohrer, E Castro, Z Hu, ATL Queiroz… - Journal of Experimental …, 2021 - rupress.org
Host resistance to Mycobacterium tuberculos is (Mtb) infection requires the activities of
multiple leukocyte subsets, yet the roles of the different innate effector cells during …
multiple leukocyte subsets, yet the roles of the different innate effector cells during …
Identification of lung innervating sensory neurons and their target specificity
Known as the gas exchange organ, the lung is also critical for responding to the aerosol
environment in part through interaction with the nervous system. The diversity and specificity …
environment in part through interaction with the nervous system. The diversity and specificity …
Eosinophils regulate intra-adipose axonal plasticity
X Meng, X Qian, X Ding, W Wang… - Proceedings of the …, 2022 - National Acad Sciences
Sympathetic innervation regulates energy balance, and the nerve density in the adipose
tissues changes under various metabolic states, resulting in altered neuronal control and …
tissues changes under various metabolic states, resulting in altered neuronal control and …
[HTML][HTML] Airway innervation and plasticity in asthma
LEM Kistemaker, YS Prakash - Physiology, 2019 - journals.physiology.org
Airway nerves represent a mechanistically and therapeutically important aspect that requires
better highlighting in the context of diseases such as asthma. Altered structure and function …
better highlighting in the context of diseases such as asthma. Altered structure and function …
[HTML][HTML] Neuroimmune pathophysiology in asthma
GF Pavón-Romero, NH Serrano-Pérez… - Frontiers in Cell and …, 2021 - frontiersin.org
Asthma is a chronic inflammation of lower airway disease, characterized by bronchial
hyperresponsiveness. Type I hypersensitivity underlies all atopic diseases including allergic …
hyperresponsiveness. Type I hypersensitivity underlies all atopic diseases including allergic …
[HTML][HTML] Macrophages orchestrate airway inflammation, remodeling, and resolution in asthma
RD Britt Jr, A Ruwanpathirana, ML Ford… - International journal of …, 2023 - mdpi.com
Asthma is a heterogenous chronic inflammatory lung disease with endotypes that manifest
different immune system profiles, severity, and responses to current therapies. Regardless of …
different immune system profiles, severity, and responses to current therapies. Regardless of …