Therapeutic potential and main methods of obtaining selenium nanoparticles

EG Varlamova, EA Turovsky, EV Blinova - International journal of …, 2021 - mdpi.com
This review presents the latest data on the importance of selenium nanoparticles in human
health, their use in medicine, and the main known methods of their production by various …

Animal models of drug-induced pulmonary fibrosis: an overview of molecular mechanisms and characteristics

S Li, J Shi, H Tang - Cell Biology And Toxicology, 2022 - Springer
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease characterized by
progressive loss of pulmonary function. Drug-induced interstitial lung disease has been …

Thymol protects against bleomycin-induced pulmonary fibrosis via abrogation of oxidative stress, inflammation, and modulation of miR-29a/TGF-β and PI3K/Akt …

RM Hussein, ESA Arafa, SA Raheem, WR Mohamed - Life sciences, 2023 - Elsevier
Idiopathic pulmonary fibrosis is a terminal lung ailment that shares several pathological and
genetic mechanisms with severe COVID-19. Thymol (THY) is a dietary compound found in …

Lung pneumonitis and fibrosis in cancer therapy: a review on cellular and molecular mechanisms

C Xu, Z Shang, M Najafi - Current Drug Targets, 2022 - ingentaconnect.com
Fibrosis and pneumonitis are the most important side effects of lung tissue following cancer
therapy. Radiotherapy and chemotherapy by some drugs, such as bleomycin, can induce …

The influence of PM2. 5 on lung injury and cytokines in mice

J Yang, Y Chen, Z Yu, H Ding… - Experimental and …, 2019 - spandidos-publications.com
Exposure to particulate matter≤ 2.5 µm in diameter (PM2. 5) profoundly affects human
health. However, the role of PM2. 5 on lung injury and cytokine levels in mice is currently …

The hepatoprotective effect of piperine against thioacetamide-induced liver fibrosis in mice: The involvement of miR-17 and TGF-β/smads pathways

AM Abdelhamid, A Selim, MA Zaafan - Frontiers in molecular …, 2021 - frontiersin.org
Liver fibrosis is characterized by a series of events including activation of quiescent hepatic
stellate cells (HSCs) into proinflammatory, contractile, and fibrogenic myofibroblasts, which …

Protective effect of dapsone against bleomycin-induced lung fibrosis in rat

H Yousefi-Manesh, T Noori, MH Asgardoon… - Experimental and …, 2022 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial disease of the lung tissue that
causes symptoms such as coughing and asthma. It is caused by inflammatory factors and …

Amitriptyline attenuates bleomycin-induced pulmonary fibrosis: Modulation of the expression of NF-κβ, iNOS, and Nrf2

MA Zaafan, AR Haridy, AM Abdelhamid - … -Schmiedeberg's archives of …, 2019 - Springer
Amitriptyline is a tricyclic antidepressant that was suggested to have antifibrotic potential.
The current study aimed to investigate the modulatory effects of amitriptyline on bleomycin …

[HTML][HTML] Pyrrolidine dithiocarbamate inhibits mouse acute kidney injury induced by diclofenac by targeting oxidative damage, cytokines and NF-κB activity

SM Borghi, V Fattori, KW Ruiz-Miyazawa, MM Bertozzi… - Life sciences, 2018 - Elsevier
Aims Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used and effective anti-
inflammatories despite the well-known side effects such as gastrointestinal damage, acute …

Combination of Salvia miltiorrhiza and ligustrazine attenuates bleomycin-induced pulmonary fibrosis in rats via modulating TNF-α and TGF-β

C Huang, X Wu, S Wang, W Wang, F Guo, Y Chen… - Chinese Medicine, 2018 - Springer
Background Idiopathic pulmonary fibrosis (IPF), a chronic, progressive, fibrosing interstitial
lung disease, is associated with extremely poor prognosis, and lacks effective treatment. The …