Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Molecular changes in malignant tissue can lead to an increase in the expression levels of
various proteins or receptors that can be used to target the disease. In oncology, diagnostic …

Protein-based conjugates are valuable constructs for a variety of applications. Conjugation
of proteins to fluorophores is commonly used to study their cellular localization and the …

Bioorthogonal chemical reactions have emerged as convenient and rapid methods for
incorporating unnatural functionality into living systems. Different prototype reactions have …

Magnetic resonance imaging (MRI) is a powerful and indispensable tool in medical
research, clinical diagnosis, and patient care due to its high spatial resolution and non …

Sortase‐mediated ligation (SML) has emerged as a powerful and versatile methodology for
site‐specific protein conjugation, functionalization/labeling, immobilization, and design of …

Creation of functional protein bioconjugates demands methods for attaching a diverse array
of probes to target proteins with high specificity, under mild conditions. The sortase A …

A generic site‐specific conjugation method that generates a homogeneous product is of
utmost importance in tracer development for molecular imaging and therapy. We explored …

Antibodies and their derivatives radiolabelled with positron-and gamma-emitting
radiometals enable sensitive and quantitative molecular Positron Emission Tomography …

Liver accumulation of nanoparticles is a major challenge in nanoparticle-mediated delivery
as it can reduce the delivery of the nanoparticles to their intended site and lead to liver …