The current in vivo models for the utility and discovery of new potential anti-leishmanial
drugs targeting Cutaneous Leishmaniasis (CL) differ vastly in their immunological …

Nonhuman primates are important laboratory animals for biomedical, pharmacology, and
toxicology research. To effectively use primates as models, their gross and histologic …

Leishmaniasis is a protozoan parasitic disease endemic to the tropical and subtropical
regions of the world, with three major clinical forms, self‐healing cutaneous leishmaniasis …

The conservative nature of animal evolution makes animal models the ideal tool for learning
about human biology. The Handbook of Laboratory Animal Science, Second Edition: Animal …

Infection with Leishmania major parasites results in the development of cutaneous ulcerative
lesions on the skin. We investigated the protective potential of a single, recombinant histone …

Leishmaniases spp are protozoan parasites of the Trypanosomatidae family that cause
disease in humans and animals. In general, infections with these parasites can be divided …

Biomedical research involving animal models continues to provide important insights into
disease pathogenesis and treatment of diseases that impact human health. In particular …

There is a critical need for an alternative nonhuman primate model for inhalational anthrax
infection because of the increasingly limited supply and cost of the current model. This report …

Visceral leishmaniasis represents a serious public health concern in endemic regions and is
rapidly emerging as an opportunistic infection in HIV patients. The disease is difficult to …

In 2001, a bioterrorism attack involving Bacillus anthracis spore-laced letters resulted in 22
cases of inhalation anthrax, with five fatalities. This incident identified gaps in our health care …