[HTML][HTML] Coagulopathy and thrombosis as a result of severe COVID-19 infection: a microvascular focus
UK Katneni, A Alexaki, RC Hunt… - Thrombosis and …, 2020 - thieme-connect.com
Coronavirus disease of 2019 (COVID-19) is the clinical manifestation of the respiratory
infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While …
infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While …
[HTML][HTML] Status of major hemostatic components in the setting of COVID-19: the effect on endothelium, platelets, coagulation factors, fibrinolytic system, and …
The coagulation, fibrinolytic, anticoagulation, and complement systems are in delicate
balance with the vessel wall endothelium ensuring appropriate hemostasis. Coagulopathy …
balance with the vessel wall endothelium ensuring appropriate hemostasis. Coagulopathy …
[HTML][HTML] The effects of coagulation factors on the risk of endometriosis: a Mendelian randomization study
Y Li, H Liu, S Ye, B Zhang, X Li, J Yuan, Y Du, J Wang… - BMC medicine, 2023 - Springer
Background Endometriosis is recognized as a complex gynecological disorder that can
cause severe pain and infertility, affecting 6–10% of all reproductive-aged women …
cause severe pain and infertility, affecting 6–10% of all reproductive-aged women …
[HTML][HTML] The ADAMTS13–VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension
Chronic thromboembolic pulmonary hypertension (CTEPH) is an important consequence of
pulmonary embolism that is associated with abnormalities in haemostasis. We investigated …
pulmonary embolism that is associated with abnormalities in haemostasis. We investigated …
Timing during translation matters: synonymous mutations in human pathologies influence protein folding and function
R Rauscher, Z Ignatova - Biochemical Society Transactions, 2018 - portlandpress.com
Ribosomes translate mRNAs with non-uniform speed. Translation velocity patterns are a
conserved feature of mRNA and have evolved to fine-tune protein folding, expression and …
conserved feature of mRNA and have evolved to fine-tune protein folding, expression and …
[HTML][HTML] Impact of the von Willebrand factor-ADAMTS-13 axis on the risk of future venous thromboembolism
MS Edvardsen, ES Hansen, T Ueland, P Aukrust… - Journal of Thrombosis …, 2023 - Elsevier
Background von Willebrand factor (VWF) and its cleaving protease, ADAMTS-13, form a
pivotal axis that regulates hemostasis. However, the role of the VWF-ADAMTS-13 axis in the …
pivotal axis that regulates hemostasis. However, the role of the VWF-ADAMTS-13 axis in the …
Research progress on the pathogenesis of CTEPH
L Yan, X Li, Z Liu, Z Zhao, Q Luo, Q Zhao, Q Jin… - Heart Failure …, 2019 - Springer
Chronic thromboembolic pulmonary hypertension (CTEPH) is an established long-term
complication of pulmonary thromboembolism (PTE). However, studies have shown that …
complication of pulmonary thromboembolism (PTE). However, studies have shown that …
[HTML][HTML] Missense Variants of von Willebrand Factor in the Background of COVID-19 Associated Coagulopathy
Z Elek, E Losoncz, K Maricza, Z Fülep, Z Bánlaki… - Genes, 2023 - mdpi.com
COVID-19 associated coagulopathy (CAC), characterized by endothelial dysfunction and
hypercoagulability, evokes pulmonary immunothrombosis in advanced COVID-19 cases …
hypercoagulability, evokes pulmonary immunothrombosis in advanced COVID-19 cases …
[HTML][HTML] Verification of the role of ADAMTS13 in the cardiovascular disease using two-sample Mendelian randomization
Z Ye, J Zheng - Frontiers in genetics, 2021 - frontiersin.org
Objective ADAMTS13 plays a crucial role in several diseases. Many observational studies
have reported the relationship between ADAMTS13 and some cardiovascular diseases but …
have reported the relationship between ADAMTS13 and some cardiovascular diseases but …
Single-and multimarker genome-wide scans evidence novel genetic risk modifiers for venous thromboembolism
M Herrera-Rivero, M Stoll… - Thrombosis and …, 2021 - thieme-connect.com
Previous genome-wide association studies (GWASs) have established several susceptibility
genes for venous thromboembolism (VTE) and suggested many others. However, a large …
genes for venous thromboembolism (VTE) and suggested many others. However, a large …