Long non-coding RNA: Classification, biogenesis and functions in blood cells

S Dahariya, I Paddibhatla, S Kumar… - Molecular …, 2019 - Elsevier
While there exist some long non-coding RNAs (lncRNAs) that are structurally similar to
mRNAs (capped, spliced, poly a tail), not all of the lncRNAs exhibit these features …

[图书][B] Hematology E-Book: Basic Principles and Practice

R Hoffman, EJ Benz, LE Silberstein, H Heslop, J Weitz… - 2022 - books.google.com
Extensively revised, comprehensive content from leading global contributors ensures that
Hematology, 8th Edition, remains your# 1 choice for expert guidance in all areas of this …

Blood platelet formation at a glance

J Boscher, I Guinard, A Eckly, F Lanza… - Journal of cell …, 2020 - journals.biologists.com
The main function of blood platelets is to ensure hemostasis and prevent hemorrhages. The
1011 platelets needed daily are produced in a well-orchestrated process. However, this …

MicroRNAs as regulators and effectors of hematopoietic transcription factors

MJ Kim, CI Civin, TJ Kingsbury - Wiley Interdisciplinary Reviews …, 2019 - Wiley Online Library
Hematopoiesis is a highly‐regulated development process orchestrated by lineage‐specific
transcription factors that direct the generation of all mature blood cells types, including red …

Apoptosis in megakaryocytes: Safeguard and threat for thrombopoiesis

S Yang, L Wang, Y Wu, A Wu, F Huang… - Frontiers in …, 2023 - frontiersin.org
Platelets, generated from precursor megakaryocytes (MKs), are central mediators of
hemostasis and thrombosis. The process of thrombopoiesis is extremely complex, regulated …

Platelet microRNA expression and association with platelet maturity and function in patients with essential thrombocythemia

JQD Tran, OH Pedersen, ML Larsen, EL Grove… - Platelets, 2020 - Taylor & Francis
Essential thrombocythemia (ET) is characterized by persistently elevated platelet counts and
an increased risk of thromboembolic events. Dysregulated expression of small noncoding …

Implication of microRNAs in carcinogenesis with emphasis on hematological malignancies and clinical translation

Z Gaál - International Journal of Molecular Sciences, 2022 - mdpi.com
MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs, that are
involved in the multistep process of carcinogenesis, contributing to all established hallmarks …

LncRNAs in blood cells: Roles in cell development and potential pathogenesis in hematological malignancies

X Guan, Y Sun, C Zhang - Critical Reviews in Oncology/Hematology, 2022 - Elsevier
Long non-coding RNA (LncRNA) is a class of non-coding RNA comprising more than 200
nucleotides. Several studies report that LncRNAs are widely involved in biological …

Roles of non-coding RNA in megakaryocytopoiesis and thrombopoiesis: new target therapies in ITP

W Li, Y Lv, Y Sun - Platelets, 2023 - Taylor & Francis
Noncoding RNAs (ncRNAs) are a group of RNA molecules that cannot encode proteins, and
a better understanding of the complex interaction networks coordinated by ncRNAs will …

Mercury chloride impacts on the development of erythrocytes and megakaryocytes in mice

J He, Y Zhao, T Zhu, P Xue, W Zheng, Y Yao, W Qu… - Toxics, 2021 - mdpi.com
Inorganic mercury (Hg2+) is a highly toxic heavy metal. The aim of this study was to
investigate the impact of Hg2+ on the development of erythrocytes and megakaryocytes …