The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Brain oxytocin: how puzzle stones from animal studies translate into psychiatry

V Grinevich, ID Neumann - Molecular psychiatry, 2021 - nature.com
The neuropeptide oxytocin has attracted great attention of the general public, basic
neuroscience researchers, psychologists, and psychiatrists due to its profound pro-social …

Balance of brain oxytocin and vasopressin: implications for anxiety, depression, and social behaviors

ID Neumann, R Landgraf - Trends in neurosciences, 2012 - cell.com
Oxytocin and vasopressin are regulators of anxiety, stress-coping, and sociality. They are
released within hypothalamic and limbic areas from dendrites, axons, and perikarya …

The consequences of early‐life adversity: neurobiological, behavioural and epigenetic adaptations

S Maccari, HJ Krugers… - Journal of …, 2014 - Wiley Online Library
During the perinatal period, the brain is particularly sensitive to remodelling by
environmental factors. Adverse early‐life experiences, such as stress exposure or …

The neuropeptide oxytocin facilitates pro-social behavior and prevents social avoidance in rats and mice

M Lukas, I Toth, SO Reber, DA Slattery… - …, 2011 - nature.com
Social avoidance and social phobia are core symptoms of various psychopathologies but
their underlying etiology remains poorly understood. Therefore, this study aims to reveal pro …

Oxytocin signaling in the lateral septum prevents social fear during lactation

R Menon, T Grund, I Zoicas, F Althammer, D Fiedler… - Current Biology, 2018 - cell.com
Oxytocin (OXT)-mediated behavioral responses to social and stressful cues have
extensively been studied in male rodents. Here, we investigated the capacity of brain OXT …

Breaking the loop: oxytocin as a potential treatment for drug addiction

IS McGregor, MT Bowen - Hormones and behavior, 2012 - Elsevier
Drug use typically occurs within a social context, and social factors play an important role in
the initiation, maintenance and recovery from addictions. There is now accumulating …

[HTML][HTML] Oxytocin and social motivation

I Gordon, C Martin, R Feldman, JF Leckman - Developmental cognitive …, 2011 - Elsevier
Humans are fundamentally social creatures who are 'motivated'to be with others. In this
review we examine the role of oxytocin (OT) as it relates to social motivation. OT is …

Sex differences in oxytocin receptor binding in forebrain regions: correlations with social interest in brain region-and sex-specific ways

KM Dumais, R Bredewold, TE Mayer… - Hormones and …, 2013 - Elsevier
Social interest reflects the motivation to approach a conspecific for the assessment of social
cues and is measured in rats by the amount of time spent investigating conspecifics. Virgin …

Developmental perspectives on oxytocin and vasopressin

EAD Hammock - Neuropsychopharmacology, 2015 - nature.com
The related neuropeptides oxytocin and vasopressin are involved in species-typical
behavior, including social recognition behavior, maternal behavior, social bonding …