Centromere: A Trojan horse for genome stability

A Scelfo, D Fachinetti - DNA repair, 2023 - Elsevier
Centromeres play a key role in the maintenance of genome stability to prevent
carcinogenesis and diseases. They are specialized chromosome loci essential to ensure …

Unlocking plant genetics with telomere-to-telomere genome assemblies

V Garg, A Bohra, M Mascher, M Spannagl, X Xu… - Nature …, 2024 - nature.com
Contiguous genome sequence assemblies will help us to realize the full potential of crop
translational genomics. Recent advances in sequencing technologies, especially long-read …

The structure, function, and evolution of plant centromeres

M Naish, IR Henderson - Genome Research, 2024 - genome.cshlp.org
Centromeres are essential regions of eukaryotic chromosomes responsible for the formation
of kinetochore complexes, which connect to spindle microtubules during cell division …

[HTML][HTML] HEI10 coarsening, chromatin and sequence polymorphism shape the plant meiotic recombination landscape

C Morgan, M Howard, IR Henderson - Current Opinion in Plant Biology, 2024 - Elsevier
Meiosis is a conserved eukaryotic cell division that produces spores required for sexual
reproduction. During meiosis, chromosomes pair and undergo programmed DNA double …

Alternating between even and odd ploidy levels switches on and off the recombination control, even near the centromeres

F Boideau, V Huteau, L Maillet, A Brunet… - The Plant …, 2024 - academic.oup.com
Meiotic recombination is a key biological process in plant evolution and breeding, as it
generates genetic diversity in each generation through the formation of crossovers (COs) …

Centromere-proximal suppression of meiotic crossovers in Drosophila is robust to changes in centromere number, repetitive DNA content, and centromere-clustering

NM Pazhayam, LK Frazier, J Sekelsky - Genetics, 2024 - academic.oup.com
Accurate segregation of homologous chromosomes during meiosis depends on both the
presence and the regulated placement of crossovers (COs). The centromere effect, or CO …

Varying recombination landscapes between individuals are driven by polymorphic transposable elements

Y Huang, Y Gao, K Ly, L Lin, JP Lambooij, EG King… - bioRxiv, 2024 - biorxiv.org
Meiotic recombination is a prominent force shaping genome evolution, and understanding
the causes for varying recombination landscapes within and between species has remained …

The role of methylation and structural variants in shaping the recombination landscape of barley

FA Casale, C Arlt, M Kuehl, J Li, J Engelhorn, T Hartwig… - bioRxiv, 2024 - biorxiv.org
Meiotic recombination is not only a key mechanism for sexual adaptation in eukaryotes but
crucial for the accumulation of beneficial alleles in breeding populations. The effective …