Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

[HTML][HTML] Understanding how microorganisms respond to acid pH is central to their control and successful exploitation

PA Lund, D De Biase, O Liran, O Scheler… - Frontiers in …, 2020 - frontiersin.org
Microbes from the three domains of life, Bacteria, Archaea, and Eukarya, share the need to
sense and respond to changes in the external and internal concentrations of protons. When …

Candida albicans-Biology, molecular characterization, pathogenicity, and advances in diagnosis and control–An update

M Dadar, R Tiwari, K Karthik, S Chakraborty… - Microbial …, 2018 - Elsevier
Candida albicans is an emerging multidrug-resistant fungal pathogen representing an
important source of invasive disease in humans and generating high healthcare costs …

Building a genome-based understanding of bacterial pH preferences

J Ramoneda, E Stallard-Olivera, M Hoffert… - Science …, 2023 - science.org
The environmental preferences of many microbes remain undetermined. This is the case for
bacterial pH preferences, which can be difficult to predict a priori despite the importance of …

Mechanism of Candida pathogenesis: revisiting the vital drivers

IE Mba, EI Nweze - European Journal of Clinical Microbiology & Infectious …, 2020 - Springer
Candida is the most implicated fungal pathogen in the clinical setting. Several factors play
important roles in the pathogenesis of Candida spp. Multiple transcriptional circuits …

[HTML][HTML] Environmental pH modulation by pathogenic fungi as a strategy to conquer the host

S Vylkova - PLoS pathogens, 2017 - journals.plos.org
The ability of microorganisms to sense and adapt to changes in the environment is essential
to their survival. This is particularly important for species with an intimate association with …

[HTML][HTML] Host's Immunity and Candida Species Associated with Denture Stomatitis: A Narrative Review

P Le Bars, AA Kouadio, ON Bandiaky, L Le Guéhennec… - Microorganisms, 2022 - mdpi.com
Denture-related Candida stomatitis, which has been described clinically in the literature, is
either localized or generalized inflammation of the oral mucosa in connection with a …

[HTML][HTML] Adapting to survive: How Candida overcomes host-imposed constraints during human colonization

R Alves, C Barata-Antunes, M Casal, AJP Brown… - PLoS …, 2020 - journals.plos.org
Successful human colonizers such as Candida pathogens have evolved distinct strategies
to survive and proliferate within the human host. These include sophisticated mechanisms to …

Multiple alternative carbon pathways combine to promote Candida albicans stress resistance, immune interactions, and virulence

RB Williams, MC Lorenz - MBio, 2020 - Am Soc Microbiol
The phagocytic cells of the innate immune system are an essential first line of antimicrobial
defense, and yet Candida albicans, one of the most problematic fungal pathogens, is …