The cascade of metastasis in tumor cells, exhibiting organ-specific tendencies, may occur at
numerous phases of the disease and progress under intense evolutionary pressures. Organ …

With the rapid increase in the incidence of cervical cancer, anal cancer and other cancers,
human papillomavirus (HPV) infection has become a growing concern. Persistent infection …

Human tumors are intricate ecosystems composed of diverse genetic clones and malignant
cell states that evolve in a complex tumor micro-environment. Single-cell RNA-sequencing …

Epithelial-to-mesenchymal transition (EMT) is a process by which cells lose their epithelial
characteristics and gain mesenchymal phenotypes. In cancer, EMT is thought to drive tumor …

The incidence of human papillomavirus-positive (HPV+) oropharyngeal squamous cell
carcinoma (OPSCC) is rising rapidly and has exceeded cervical cancer to become the most …

Abstract Human Papilloma Virus (HPV)-associated oropharyngeal squamous cell cancer
(OPSCC) represents an OPSCC subgroup with an overall good prognosis with a rising …

Head and neck squamous cell carcinoma is the sixth most common cancer worldwide and
has high heterogeneity and unsatisfactory outcomes. To better characterize the tumor …

Abstract The World Health Organisation recognised human papillomavirus (HPV) as the
cause of multiple cancers, including head and neck cancers. HPV is a double-stranded DNA …

Macrophages played an important role in the progression and treatment of head and neck
squamous cell carcinoma (HNSCC). We employed weighted gene co-expression network …

Cervical squamous cell carcinoma (CSCC) exhibits a limited response to immune-
checkpoint blockade. Here we conducted a multiomic analysis encompassing single-cell …