Natural product compounds have recently attracted significant attention from the scientific
community for their potent effects against inflammation-driven diseases, including cancer. A …

Signal Transducer and Activator of Transcription (STAT) pathway is connected upstream
with Janus kinases (JAK) family protein and capable of integrating inputs from different …

Triple-negative breast cancer (TNBC) is a subtype of human breast cancer with one of the
worst prognoses, with no targeted therapeutic strategies currently available. Regulated cell …

Ovarian cancer is one of the leading causes of death in patients with gynecological
malignancy. Despite optimal cytoreductive surgery and platinum-based chemotherapy …

Natural compounds, in recent years, have attracted significant attention for their use in the
prevention and treatment of diverse chronic diseases as they are devoid of major toxicities …

Rutin is one of the most common dietary polyphenols found in vegetables, fruits, and other
plants. It is metabolized by the mammalian gut microbiota and absorbed from the intestines …

JAK/STAT signaling pathway is one of the important regulatory signaling cascades for the
myriad of cellular processes initiated by various types of ligands such as growth factors …

Introduction Epithelial-mesenchymal transition (EMT) is a process of transdifferentiation
where epithelial cells attain mesenchymal phenotype to gain invasive properties and thus …

Signal transducer and activator of transcription 3 (STAT3) is one of the crucial transcription
factors, responsible for regulating cellular proliferation, cellular differentiation, migration …

Novel and alternative options are being adopted to combat the initiation and progression of
human cancers. One of the approaches is the use of molecules isolated from traditional …