Pinpointing the precise stimulation targets for brain rehabilitation in early-stage Parkinson's disease

H Lu, J Li, L Zhang, L Meng, Y Ning, T Jiang - BMC neuroscience, 2023 - Springer
Background Transcranial magnetic stimulation (TMS) is increasingly used as a promising
non-pharmacological treatment for Parkinson's disease (PD). Scalp-to-cortex distance …

Dynamic changes of region-specific cortical features and scalp-to-cortex distance: implications for transcranial current stimulation modeling

H Lu, J Li, L Zhang, SSM Chan, LCW Lam… - Journal of …, 2021 - Springer
Background Transcranial current stimulation in rehabilitation is a fast-growing field featured
with computational and biophysical modeling. Cortical features and scalp-to-cortex distance …

Using gamma-band transcranial alternating current stimulation (tACS) to improve sleep quality and cognition in patients with mild neurocognitive disorders due to …

H Lu, J Li, NS Yang, LCW Lam, SL Ma, YK Wing… - Plos one, 2023 - journals.plos.org
Background Sleep disturbances are highly prevalent in patients with age-related
neurodegenerative diseases, which severely affect cognition and even lead to accumulated …

Decoding MRI-informed brain age using mutual information

J Li, LCW Lam, H Lu - Insights into Imaging, 2024 - Springer
Objective We aimed to develop a standardized method to investigate the relationship
between estimated brain age and regional morphometric features, meeting the criteria for …

Quantifying age-associated cortical complexity of left dorsolateral prefrontal cortex with multiscale measurements

H Lu - Journal of Alzheimer's Disease, 2020 - content.iospress.com
Background: Cortical complexity plays a central role in the diagnosis and prognosis of age-
related diseases. However, little is known about the regional cortical complexity in the …

Ethnic differences in the effects of apolipoprotein E ɛ4 and vascular risk factors on accelerated brain aging

Y Im, SH Kang, G Park, H Yoo, MY Chun… - Brain …, 2024 - academic.oup.com
The frequency of the apolipoprotein E ɛ4 allele and vascular risk factors differs among
ethnic groups. We aimed to assess the combined effects of apolipoprotein E ɛ4 and …

Aberrant interhemispheric functional connectivity within default mode network and its relationships with neurocognitive features in cognitively normal APOE ε 4 elderly …

H Lu, SL Ma, SWH Wong, CWC Tam… - International …, 2017 - cambridge.org
Background: Default mode network (DMN) is vulnerable to the effects of APOE genotype.
Given the reduced brain volumes and APOE ε 4-related brain changes in elderly carriers, it …

Cortical covariance networks in ageing: cross-sectional data from the Irish Longitudinal Study on Ageing (TILDA)

D Carey, H Nolan, RA Kenny, J Meaney - Neuropsychologia, 2019 - Elsevier
Ageing is associated with widespread alterations to the brain's anatomy and to attendant
cortical networks. Yet, few studies to date have indexed anatomical covariance network …

MRI-informed machine learning-driven brain age models for classifying mild cognitive impairment converters

H Lu, J Li - Journal of Central Nervous System Disease, 2024 - journals.sagepub.com
BACKGROUND Brain age model, including estimated brain age and brain-predicted age
difference (brain-PAD), has shown great potentials for serving as imaging markers for …

Hippocampal volume loss, brain amyloid accumulation, and APOE status in cognitively intact elderly subjects

S Haller, ML Montandon, C Rodriguez… - Neurodegenerative …, 2020 - karger.com
Background: Hippocampal volume loss (HVL), PET-documented brain amyloid
accumulation, and APOE-ε4 status are predictive biomarkers of the transition from mild …