Epithelial-to-mesenchymal transition (EMT) mechanism is responsible for metastasis and
migration of cancer cells to neighboring cells and tissues. Morphologically, epithelial cells …

AXL is a member of the TAM (TYRO3, AXL, and MERTK) receptor tyrosine kinases family
(RTKs), and its abnormal expression has been linked to clinicopathological features and …

Esophageal cancer (EC) is the sixth leading cause of cancer-related deaths worldwide.
Western medicine has played a leading role in its treatment, but its prognosis remains …

Collective detachment of cancer cells at the invading front could generate efficient metastatic
spread. However, how cancer cell clusters shed from the leading front remains unknown …

Background Colorectal cancer (CRC) has a high morbidity and mortality worldwide. 20 (S)-
ginsenoside Rh2 (G-Rh2) is a natural compound extracted from ginseng, which exhibits …

Abstract Growth arrest specific 6 (GAS6) encodes a protein that serves as a ligand for AXL
receptor tyrosine kinase and stimulates cell proliferation. Notably, an antisense RNA …

Flaviviruses, as critically important pathogens, are still major public health problems all over
the world. For instance, the evolution of ZIKV led to large-scale outbreaks in the Yap island …

Methoxydalbergione (4‑MD) can inhibit the progression of certain types of cancer; however,
its effects on esophageal cancer (EC) remain unclear. The present study aimed to …

Esophageal squamous cell carcinoma (ESCC) is a malignant tumor of the digestive tract
with strong migratory and invasive abilities. Gas6 is closely associated with the progression …

Zika virus (ZIKV), a flavivirus that is mainly transmitted by A. aegypti and A. albopictus and
sexual transmission, has been documented and described. The ZIKV RNA detection in the …