Recent advances refining galactooligosaccharide production from lactose

A Gosling, GW Stevens, AR Barber, SE Kentish… - Food chemistry, 2010 - Elsevier
The production of prebiotic galactooligosaccharides (GOS) by the β-galactosidase catalysed
conversion of lactose has become commercially important. Yet it remains a challenge to …

β-Galactosidases: A great tool for synthesizing galactose-containing carbohydrates

L Lu, L Guo, K Wang, Y Liu, M Xiao - Biotechnology advances, 2020 - Elsevier
Abstract β-Galactosidases, an important class of glycosidases, naturally catalyze the
hydrolysis of β-galactosidic bonds in oligosaccharides and polysaccharides. Traditionally …

Influence of side chain conformation on the activity of glycosidase inhibitors

PS Tseng, C Ande, KW Moremen… - Angewandte Chemie, 2023 - Wiley Online Library
Substrate side chain conformation impacts reactivity during glycosylation and glycoside
hydrolysis and is restricted by many glycosidases and glycosyltransferases during catalysis …

Application of the PM6 semi-empirical method to modeling proteins enhances docking accuracy of AutoDock

Z Bikadi, E Hazai - Journal of cheminformatics, 2009 - Springer
Background Molecular docking methods are commonly used for predicting binding modes
and energies of ligands to proteins. For accurate complex geometry and binding energy …

Biochemical characterization of a novel thermostable β-glucosidase from Dictyoglomus turgidum

FA Fusco, G Fiorentino, E Pedone, P Contursi… - International journal of …, 2018 - Elsevier
Dtur_0462 gene from the hypertermophilic bacterium Dictyoglomus turgidum, encoding a β-
glucosidase, was synthetically produced and expressed in Escherichia coli BL21 (DE3)-RIL …

Imino sugars and glycosyl hydrolases: historical context, current aspects, emerging trends

AE Stütz, TM Wrodnigg - Advances in carbohydrate chemistry and …, 2011 - Elsevier
Forty years of discoveries and research on imino sugars, which are carbohydrate analogues
having a basic nitrogen atom instead of oxygen in the sugar ring and, acting as potent …

Structural analysis, enzymatic characterization, and catalytic mechanisms of β‐galactosidase from Bacillus circulans sp. alkalophilus

M Maksimainen, S Paavilainen, N Hakulinen… - The FEBS …, 2012 - Wiley Online Library
Crystal structures of native and α‐d‐galactose‐bound Bacillus circulans sp. alkalophilusβ‐
galactosidase (Bca‐β‐gal) were determined at 2.40 and 2.25 Å resolutions, respectively …

Crystal structures of Paenibacillus polymyxa β-glucosidase B complexes reveal the molecular basis of substrate specificity and give new insights into the catalytic …

P Isorna, J Polaina, L Latorre-García, FJ Cañada… - Journal of molecular …, 2007 - Elsevier
Bacteria species involved in degradation of cellulosic substrates produce a variety of
enzymes for processing related compounds along the hydrolytic pathway. Paenibacillus …

Crystal structure at 1.1 Å resolution of an insect myrosinase from Brevicoryne brassicae shows its close relationship to β-glucosidases

H Husebye, S Arzt, WP Burmeister, FV Härtel… - Insect biochemistry and …, 2005 - Elsevier
The aphid Brevicoryne brassicae is a specialist feeding on Brassicaceae plants. The insect
has an intricate defence system involving a β-d-thioglucosidase (myrosinase) that …

Crystal structures of Trichoderma reesei β-galactosidase reveal conformational changes in the active site

M Maksimainen, N Hakulinen, JM Kallio… - Journal of structural …, 2011 - Elsevier
We have determined the crystal structure of Trichoderma reesei (Hypocrea jecorina) β-
galactosidase (Tr-β-gal) at a 1.2 Å resolution and its complex structures with galactose, IPTG …