Nanotechnology plays a significant role in drug development. As carriers, polymeric
nanoparticles can deliver vaccine antigens, proteins, and drugs to the desired site of action …

The main limitation in engineering in vitro tissues is the lack of a sufficient blood vessel
system—the vascularization. In vivo almost all tissues are supplied by these endothelial cell …

Tissue engineering holds great promise for regeneration and repair of diseased tissues,
making the development of tissue engineering scaffolds a topic of great interest in …

Biomaterials play a critical role in engineering of tissue constructs, working as an artificial
extracellular matrix to support regeneration. Because the elastic stretchability is a major …

Elastomeric, fully degradable, and biocompatible biomaterials are rare, with current options
presenting significant limitations in terms of ease of functionalization and tunable …

Extracellular matrix (ECM) is a complex cellular environment consisting of proteins,
proteoglycans, and other soluble molecules. ECM provides structural support to mammalian …

Tissue engineering is currently limited by the inability to adequately vascularize tissues in
vitro or in vivo. Issues of nutrient perfusion and mass transport limitations, especially oxygen …

Hydrogels are the three-dimensional network structures obtained from a class of synthetic or
natural polymers which can absorb and retain a significant amount of water. Hydrogels are …

Poly (glycerol sebacate)(PGS) is a biodegradable polymer increasingly used in a variety of
biomedical applications. This polyester is prepared by polycondensation of glycerol and …

Although 3D bio-printing technology has great potential in creating complex tissues with
multiple cell types and matrices, maintaining the viability of thick tissue construct for tissue …