Unlocking horse Y chromosome diversity

I Cardinali, A Giontella, A Tommasi, M Silvestrelli… - Genes, 2022 - mdpi.com
The present equine genetic variation mirrors the deep influence of intensive breeding
programs during the last 200 years. Here, we provide a comprehensive current state of …

Inbreeding depression and the probability of racing in the Thoroughbred horse

EW Hill, MA Stoffel, BA McGivney… - … of the Royal …, 2022 - royalsocietypublishing.org
Small effective population sizes and active inbreeding can lead to inbreeding depression
due to deleterious recessive mutations exposed in the homozygous state. The …

Genomic inbreeding trends, influential sire lines and selection in the global Thoroughbred horse population

BA McGivney, H Han, LR Corduff, LM Katz, T Tozaki… - Scientific Reports, 2020 - nature.com
The Thoroughbred horse is a highly valued domestic animal population under strong
selection for athletic phenotypes. Here we present a high resolution genomics-based …

Fine‐scale estimation of inbreeding rates, runs of homozygosity and genome‐wide heterozygosity levels in the Mangalarga Marchador horse breed

W Bizarria dos Santos… - Journal of Animal …, 2021 - Wiley Online Library
With the availability of high‐density SNP panels and the establishment of approaches for
characterizing homozygosity and heterozygosity sites, it is possible to access fine‐scale …

Rare and common variant discovery by whole-genome sequencing of 101 Thoroughbred racehorses

T Tozaki, A Ohnuma, M Kikuchi, T Ishige, H Kakoi… - Scientific reports, 2021 - nature.com
The Thoroughbred breed was formed by crossing Oriental horse breeds and British native
horses and is currently used in horseracing worldwide. In this study, we constructed a single …

Does inbreeding contribute to pregnancy loss in Thoroughbred horses?

JM Lawson, CA Shilton… - Equine Veterinary …, 2024 - Wiley Online Library
Background Excessive inbreeding increases the probability of uncovering homozygous
recessive genotypes and has been associated with an increased risk of retained placenta …

Thoroughbred stallion fertility is significantly associated with FKBP6 genotype but not with inbreeding or the contribution of a leading sire

C Castaneda, R Juras, J Kjöllerström… - Animal …, 2021 - Wiley Online Library
This is a follow‐up study to validate the previously detected association of the FKBP6 gene
with stallion subfertility. Using a select cohort of 150 Thoroughbred stallions with detailed …

A genome-wide scan for candidate lethal variants in Thoroughbred horses

ET Todd, PC Thomson, NA Hamilton, RA Ang… - Scientific reports, 2020 - nature.com
Domestic animal populations are often characterised by high rates of inbreeding and low
effective population sizes due to selective breeding practices. These practices can result in …

A QTL for conformation of back and croup influences lateral gait quality in Icelandic horses

MK Rosengren, H Sigurðardóttir, S Eriksson… - BMC genomics, 2021 - Springer
Background The back plays a vital role in horse locomotion, where the spine functions as a
spring during the stride cycle. A complex interaction between the spine and the muscles of …

Genome-wide selective analysis of Boer goat to investigate the dynamic Heredity evolution under different stages

Y Yuan, W Zhang, C Liu, Y He, H Zhang, L Xu, B Yang… - Animals, 2022 - mdpi.com
Simple Summary Boer goat is a world-famous meat-type goat breed that underwent long-
term artificial selection from African indigenous animals. The current study displayed the …