Carbohydrate-based macromolecular biomaterials

L Su, Y Feng, K Wei, X Xu, R Liu, G Chen - Chemical Reviews, 2021 - ACS Publications
Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …

Chitosan: A review on properties, biological activities and recent progress in biomedical applications

A Harugade, AP Sherje, A Pethe - Reactive and Functional Polymers, 2023 - Elsevier
Chitosan is a naturally occurring amino polysaccharide obtained by deacetylation of chitin
and is second most commonly used natural polymer. Its non-toxic, biocompatibility and …

Polymeric delivery of therapeutic nucleic acids

R Kumar, CF Santa Chalarca, MR Bockman… - Chemical …, 2021 - ACS Publications
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

MicroRNA delivery through nanoparticles

SWL Lee, C Paoletti, M Campisi, T Osaki… - Journal of Controlled …, 2019 - Elsevier
MicroRNAs (miRNAs) are attracting a growing interest in the scientific community due to
their central role in the etiology of major diseases. On the other hand, nanoparticle carriers …

Chitosan-based colloidal polyelectrolyte complexes for drug delivery: a review

D Wu, L Zhu, Y Li, X Zhang, S Xu, G Yang… - Carbohydrate polymers, 2020 - Elsevier
Polyelectrolyte complexes (PECs) as safe drug delivery carriers, are spontaneously formed
by mixing the oppositely charged polyelectrolyte solutions in water without using organic …

Stimuli-responsive nanomaterials for application in antitumor therapy and drug delivery

SH Pham, Y Choi, J Choi - Pharmaceutics, 2020 - mdpi.com
The new era of nanotechnology has produced advanced nanomaterials applicable to
various fields of medicine, including diagnostic bio-imaging, chemotherapy, targeted drug …

Therapeutic targeting of non-coding RNAs in cancer

O Slaby, R Laga, O Sedlacek - Biochemical journal, 2017 - portlandpress.com
The majority of the human genome encodes RNAs that do not code for proteins. These non-
coding RNAs (ncRNAs) affect normal expression of the genes, including oncogenes and …

Three-dimensional bioprinting of a full-thickness functional skin model using acellular dermal matrix and gelatin methacrylamide bioink

R Jin, Y Cui, H Chen, Z Zhang, T Weng, S Xia, M Yu… - Acta biomaterialia, 2021 - Elsevier
Abstract Treatment of full-thickness skin defects still presents a significant challenge in
clinical practice. Three-dimensional (3D) bioprinting technique offers a promising approach …

Chitosan: A versatile bio-platform for breast cancer theranostics

VS Madamsetty, S Tavakol, S Moghassemi… - Journal of Controlled …, 2022 - Elsevier
Breast cancer is considered one of the utmost neoplastic diseases globally, with a high
death rate of patients. Over the last decades, many approaches have been studied to early …

Chitosan-based nanoparticles for nucleic acid delivery: technological aspects, applications, and future perspectives

M Karayianni, T Sentoukas, A Skandalis, N Pippa… - Pharmaceutics, 2023 - mdpi.com
Chitosan is a naturally occurring polymer derived from the deacetylation of chitin, which is
an abundant carbohydrate found mainly in the shells of various marine and terrestrial …