Alzheimer's disease: risk factors and potentially protective measures

MVF Silva, CMG Loures, LCV Alves… - Journal of biomedical …, 2019 - Springer
Alzheimer's disease (AD) is the most common type of dementia and typically manifests
through a progressive loss of episodic memory and cognitive function, subsequently causing …

Nutritional patterns associated with the maintenance of neurocognitive functions and the risk of dementia and Alzheimer's disease: A focus on human studies

F Pistollato, RC Iglesias, R Ruiz, S Aparicio… - Pharmacological …, 2018 - Elsevier
Ample epidemiological evidence suggests a strong correlation among diet, lifestyle factors
and the onset and consolidation of dementia and Alzheimer's disease (AD). It has been …

Vitamin D in neurological diseases: a rationale for a pathogenic impact

R Moretti, ME Morelli, P Caruso - International journal of molecular …, 2018 - mdpi.com
It is widely known that vitamin D receptors have been found in neurons and glial cells, and
their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical …

Vitamin D cell signalling in health and disease

MJ Berridge - Biochemical and biophysical research communications, 2015 - Elsevier
Vitamin D deficiency has been linked to many human diseases such as Alzheimer's disease
(AD), Parkinson's disease (PD), multiple sclerosis (MS), hypertension and cardiovascular …

Vitamin D and neurological diseases: an endocrine view

C Di Somma, E Scarano, L Barrea… - International journal of …, 2017 - mdpi.com
Vitamin D system comprises hormone precursors, active metabolites, carriers, enzymes, and
receptors involved in genomic and non-genomic effects. In addition to classical bone-related …

Vitamin D, cognition and Alzheimer's disease: the therapeutic benefit is in the D-tails

V Landel, C Annweiler, P Millet… - Journal of Alzheimer's …, 2016 - content.iospress.com
Since its discovery during the epidemic of rickets in the early 1920s, the physiological effects
of vitamin D on calcium/phosphorus homeostasis have been thoroughly studied. Along with …

Vitamin D as a neurosteroid affecting the developing and adult brain

NJ Groves, JJ McGrath, THJ Burne - Annual review of nutrition, 2014 - annualreviews.org
Vitamin D deficiency is prevalent throughout the world, and growing evidence supports a
requirement for optimal vitamin D levels for the healthy developing and adult brain. Vitamin …

The peculiar role of vitamin D in the pathophysiology of cardiovascular and neurodegenerative diseases

M Janjusevic, G Gagno, AL Fluca, L Padoan… - Life sciences, 2022 - Elsevier
Vitamin D is a hormone with both genomic and non-genomic actions. It exerts its activity by
binding vitamin D receptor (VDR), which belongs to the superfamily of nuclear receptors and …

'Vitamin D and cognition in older adults': updated international recommendations

C Annweiler, E Dursun, F Féron… - Journal of internal …, 2015 - Wiley Online Library
Background Hypovitaminosis D, a condition that is highly prevalent in older adults aged 65
years and above, is associated with brain changes and dementia. Given the rapidly …

Vitamin D in the prevention, prediction and treatment of neurodegenerative and neuroinflammatory diseases

P Koduah, F Paul, JM Dörr - Epma Journal, 2017 - Springer
Vitamin D research has gained increased attention in recent times due to its roles beyond
bone health and calcium homeostasis, such as immunomodulation. In some parts of the …