Pharmaceutical particle technology is employed to improve poor aqueous solubility of drug
compounds that limits in vivo bioavailability owing to their low dissolution rate in the …

Hydrophobic ion pairing has emerged as a method to modulate the solubility of charged
hydrophilic molecules ranging in class from small molecules to large enzymes. Charged …

Molecular self-assembly has enabled the fabrication of biologically inspired, advanced
nanostructures as lipid-based nanovesicles (L-NVs). The oldest L-NVs, liposomes, have …

Interaction of serum proteins and nanoparticles leads to a nanoparticle–protein complex
formation that defines the rational strategy for a clinically relevant formulation for drug …

Quantum dots (QDs) are a type of nanoparticle with exceptional photobleaching-resistant
fluorescence. They are highly sought after for their potential use in various optical-based …

Introduction: The efficacy of many hydrophobic bioactives (pharmaceuticals, supplements,
and nutraceuticals) is limited due to their relatively low or highly variable bioavailability …

The aim of the present research work is to formulate lacidipine (LAC) loaded niosomes
formulation for the management of hypertension by thin film hydration technique. The …

Hydrotropy is a well-established strategy to enhance the aqueous solubility of hydrophobic
drugs, facilitating their formulation for oral and dermal delivery. However, most hydrotropes …

The field of nanomedicine offers promising new drug delivery systems with enhanced
properties. The literature has reported on the development of various nanomedicines that …

Clozapine is commonly used to treat schizophrenia but it is having issues of low oral
bioavailability (< 27%), degradation in GI environment and high hepatic first-pass …