The role of OATP1B1 and OATP1B3 transporter polymorphisms in drug disposition and response to anticancer drugs: a review of the recent literature
N Anabtawi, T Drabison, S Hu… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Members of the solute carrier family of organic anion transporting polypeptides
are responsible for the cellular uptake of a broad range of endogenous compounds and …
are responsible for the cellular uptake of a broad range of endogenous compounds and …
Association of ABCB1, ABCG2 drug transporter polymorphisms and smoking with disease risk and cytogenetic response to imatinib in chronic myeloid leukemia …
Background Despite acceptable results of imatinib in the treatment of chronic myeloid
leukemia (CML), some patients fail to acquire a complete cytogenetic response (CCyR) …
leukemia (CML), some patients fail to acquire a complete cytogenetic response (CCyR) …
Reduce drug uptake in the development of resistance
The appearance of drug resistance represents a significant problem for the clinical
management of patients with several malignancies. The lack of response culminates in more …
management of patients with several malignancies. The lack of response culminates in more …
Bioinformatics comprehensive analysis confirmed the potential involvement of SLC22A1 in lower-grade glioma progression and prognosis.
J HUI, N SUN, Y LIU, C YU, Y KE, Y CAO, A YU… - …, 2024 - search.ebscohost.com
Background: Although it has been established that the human Solute Carrier Family 22
(SLC22) functions as a cationic transporter, influencing cellular biological metabolism by …
(SLC22) functions as a cationic transporter, influencing cellular biological metabolism by …
Pharmacogenomics of Cancer Chemotherapy: Transporter Polymorphisms and Drug Response
Recent advancements in genomic sciences and precision medicine have led to improved
regulatory guidance for pharmacogenomics, particularly in the field of cancer therapies …
regulatory guidance for pharmacogenomics, particularly in the field of cancer therapies …
[HTML][HTML] The prognostic relevance of BCR-ABL1 transcript type, Sokal score and smoke as synergestic factor with complete cytogenetic response in CML patients …
D Radin, M Hamid, M Kargar… - Medical Science Journal …, 2022 - tmuj.iautmu.ac.ir
Background: In chronic myeloid leukemia (CML), the influence of BCR-ABL1 transcript type,
Sokal risk score and smoke on disease phynotype and cytogenetic response to treatment is …
Sokal risk score and smoke on disease phynotype and cytogenetic response to treatment is …