Skeletal and extraskeletal actions of vitamin D: current evidence and outstanding questions
R Bouillon, C Marcocci, G Carmeliet, D Bikle… - Endocrine …, 2019 - academic.oup.com
The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …
Current vitamin D status in European and Middle East countries and strategies to prevent vitamin D deficiency: a position statement of the European Calcified Tissue …
P Lips, KD Cashman, C Lamberg-Allardt… - European journal of …, 2019 - academic.oup.com
Vitamin D deficiency (serum 25-hydroxyvitamin D (25 (OH) D)< 50 nmol/L or 20 ng/mL) is
common in Europe and the Middle East. It occurs in< 20% of the population in Northern …
common in Europe and the Middle East. It occurs in< 20% of the population in Northern …
The bone remodelling cycle
JS Kenkre, JHD Bassett - Annals of clinical biochemistry, 2018 - journals.sagepub.com
The bone remodelling cycle replaces old and damaged bone and is a highly regulated,
lifelong process essential for preserving bone integrity and maintaining mineral …
lifelong process essential for preserving bone integrity and maintaining mineral …
Interdisciplinary management of FGF23-related phosphate wasting syndromes: a consensus statement on the evaluation, diagnosis and care of patients with X-linked …
X-linked hypophosphataemia (XLH) is the most frequent cause of hypophosphataemia-
associated rickets of genetic origin and is associated with high levels of the phosphaturic …
associated rickets of genetic origin and is associated with high levels of the phosphaturic …
Vitamin D: metabolism, molecular mechanism of action, and pleiotropic effects
S Christakos, P Dhawan, A Verstuyf… - Physiological …, 2016 - journals.physiology.org
1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …
[HTML][HTML] Gut microbiota and metabolite alterations associated with reduced bone mineral density or bone metabolic indexes in postmenopausal osteoporosis
Reduced bone mineral density (BMD) is associated with an altered microbiota in senile
osteoporosis. However, the relationship among gut microbiota, BMD and bone metabolic …
osteoporosis. However, the relationship among gut microbiota, BMD and bone metabolic …
Biology and mechanisms of action of the vitamin D hormone
JW Pike, S Christakos - Endocrinology and Metabolism Clinics, 2017 - endo.theclinics.com
Discovered many decades earlier by Mellanby, 1 McCollum and colleagues, 2 Steenbock, 3
and Windaus and colleagues, 4 vitamin D is now known through ensuing research efforts by …
and Windaus and colleagues, 4 vitamin D is now known through ensuing research efforts by …
[HTML][HTML] Maternal mineral and bone metabolism during pregnancy, lactation, and post-weaning recovery
CS Kovacs - Physiological reviews, 2016 - journals.physiology.org
During pregnancy and lactation, female physiology adapts to meet the added nutritional
demands of fetuses and neonates. An average full-term fetus contains∼ 30 g calcium, 20 g …
demands of fetuses and neonates. An average full-term fetus contains∼ 30 g calcium, 20 g …
FGF23 and its role in X-linked hypophosphatemia-related morbidity
SS Beck-Nielsen, Z Mughal, D Haffner… - Orphanet Journal of …, 2019 - Springer
Background X-linked hypophosphatemia (XLH) is an inherited disease of phosphate
metabolism in which inactivating mutations of the Phosphate Regulating Endopeptidase …
metabolism in which inactivating mutations of the Phosphate Regulating Endopeptidase …
[HTML][HTML] Coupling the activities of bone formation and resorption: a multitude of signals within the basic multicellular unit
NA Sims, TJ Martin - BoneKEy reports, 2014 - ncbi.nlm.nih.gov
Coupling between bone formation and bone resorption refers to the process within basic
multicellular units in which resorption by osteoclasts is met by the generation of osteoblasts …
multicellular units in which resorption by osteoclasts is met by the generation of osteoblasts …