Activating transcription factors, ATFs, is a family of transcription factors that activate gene
expression and transcription by recognizing and combining the cAMP response element …

Melanoma is one of the most lethal tumors with highly aggressive and metastatic properties.
Although immunotherapy and targeted therapy have certain therapeutic effects in …

Purpose The development of osteoarthritis (OA) has been linked to mechanical factors.
Studies suggest that periodic mechanical stress (PMS) may be a factor contributing to …

The skin is the largest organ of the human body and prone to various diseases, including
cancer; thus, provides the first line of defense against exogenous biological and non …

Background UBTF is an HMGB-box DNA binding protein and a necessary Pol I/Pol II basal
transcription factor. It has been found that UBTF involves in carcinogenesis and progression …

Abstract Activating transcription factor 1 (ATF1) is a crucial cellular regulator, with its
misregulation implicated in numerous cancers. As a key player in the ATF/CREB family …

Simple Summary Despite a negative SLN status, patients with Stage IIB/IIC melanoma
demonstrate poor melanoma-specific survival when compared to Stage IIIA patients. In this …

Background Several past studies have reported the overexpression of Flotillin-1 in a variety
of cancer types. Cisplatin is a chemotherapeutic drug commonly used for cancer treatment …

Recent studies have uncovered that TIPE2 is involved in the development of cancer.
However, less research has been conducted on the role of TIPE2 in melanoma. Our study …

Malignant melanoma is one of the most aggressive and lethal skin cancer. At present, the
treatment methods for melanoma have shortcomings. Glucose is the primary energy source …